Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22281426 | 0.93 | GSK3B (0.61) | GSK3BL3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL19642535 | 0.90 | GSK3B (0.65) | GSK3BL3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL19660192 | 0.84 | L3MBTL1 (0.61) | GSK3BL3MBTL1KMT2AALDH1A1MMP1 | |
| SCHEMBL29114071 | 0.84 | L3MBTL1 (0.50) | GSK3BL3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL29114079 | 0.83 | MAPT (0.53) | GSK3BL3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL29114072 | 0.82 | NPC1 (0.52) | GSK3BHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29041179 | 0.81 | KMT2A (0.82) | GSK3BL3MBTL1KMT2AALDH1A1NPC1 | |
| SCHEMBL5309587 | 0.81 | HDAC3 (0.57) | GSK3BL3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL30626939 | 0.81 | NPC1 (0.50) | GSK3BL3MBTL1KMT2AALDH1A1NPC1 | |
| SCHEMBL29114075 | 0.81 | NPC1 (0.50) | GSK3BL3MBTL1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017202816-A1 | 3-OXO-2,6-DIPHENYL-2,3-DIHYDROPYRIDAZINE-4-CARBOXAMIDES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-11-30 | — | — | WO | disclosed |