SCHEMBL1966049

SCHEMBL1966049

CCc1c(C)c(C)c(C)c(N=C=O)c1CN=C=O

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4540875 0.89 GABRA1 (0.39) GABRA1GABRB2
SCHEMBL3764900 0.81 GABRA1 (0.44) GABRA1GABRB2
SCHEMBL9250638 0.81 GABRA1 (0.44) GABRA1GABRB2
SCHEMBL3764897 0.81 GABRA1 (0.47) GABRA1GABRB2
SCHEMBL475788 0.77 GABRA1 (0.47) GABRA1GABRB2
SCHEMBL10500897 0.77 GABRA1 (0.47) GABRA1GABRB2
SCHEMBL20144 0.76 CYP3A4 (0.31)
SCHEMBL9681803 0.74 GABRA1 (0.32) GABRA1GABRB2
SCHEMBL22506800 0.74 GABRA1 (0.32) GABRA1GABRB2
SCHEMBL78796 0.74 CYP3A4 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016100148-A1 OPTICAL FIBER COATING COMPOSITION WITH NON-REACTIVE REINFORCING AGENT CORNING INCORPORATED (US) 2016-06-23 WO claimed
WO-2018024674-A1 CATIONIC WATER-DILUTABLE BINDERS ALLNEX AUSTRIA GMBH (AT) 2018-02-08 WO disclosed
EP-3102550-A1 PRIMARY COATING COMPOSITIONS WITH REINFORCING POLYMER Corning Incorporated (US) 2016-12-14 EP disclosed
EP-3092277-A2 OPTICAL FIBRE COATING WITH NON-RADIATION-CURABLE ACRYLIC HARD-SOFT BLOCK COPOLYMER Corning Inc. (US) 2016-11-16 EP disclosed
WO-2015147961-A2 OPTICAL FIBER COATING WITH NON-RADIATION-CURABLE ACRYLIC HARD-SOFT BLOCK COPOLYMER CORNING INCORPORATED (US) 2015-10-01 WO disclosed
EP-2638094-A2 IONIC POLYMERS, METHOD OF MANUFACTURE, AND USES THEREOF Segetis, Inc. (US) 2013-09-18 EP disclosed
WO-2012065120-A2 IONIC POLYMERS, METHOD OF MANUFACTURE, AND USES THEREOF SEGETIS, INC. (US) 2012-05-18 WO disclosed
EP-2334710-A1 COATING FORMULATIONS AND COMPOSITIONS BASED ON POLYAMINES, POLYOLS AND POLYISOCYANATES, AND PROCESSES OF PREPARING AND OF USING THE SAME Dow Global Technologies LLC (US) 2011-06-22 EP disclosed
WO-2010030544-A1 COATING FORMULATIONS AND COMPOSITIONS BASED ON POLYAMINES, POLYOLS AND POLYISOCYANATES, AND PROCESSES OF PREPARING AND OF USING THE SAME DOW GLOBAL TECHNOLOGIES INC. (US) 2010-03-18 WO disclosed