SCHEMBL19660697

SCHEMBL19660697

Cc1ccc2cc(-c3ccc4cc(Br)ccc4c3)ccc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.56
CYP1A2 P05177 4/20 0.56
CYP11B1 P15538 1/20 0.50
CYP11B2 P19099 1/20 0.50
MAOB P27338 3/20 0.49
TDP1 Q9NUW8 1/20 0.48
ALDH1A1 P00352 4/20 0.45
KDM4E B2RXH2 3/20 0.45
MEN1 O00255 2/20 0.45
MAPT P10636 2/20 0.45
KMT2A Q03164 2/20 0.45
MAPK1 P28482 1/20 0.43
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
SIRT2 Q8IXJ6 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18891725 0.91 CYP2A6 (0.56) CYP2A6CYP1A2CYP11B1CYP11B2MAOB
SCHEMBL1247086 0.91 CYP2A6 (0.68) CYP2A6CYP1A2MAOBTDP1ALDH1A1
SCHEMBL4585180 0.86 CYP2A6 (0.62) CYP2A6CYP1A2MAOBTDP1ALDH1A1
SCHEMBL13152961 0.86 CYP2A6 (0.62) CYP2A6CYP1A2MAOBTDP1ALDH1A1
SCHEMBL16520506 0.86 CYP2A6 (0.62) CYP2A6CYP1A2CYP11B1CYP11B2ALDH1A1
SCHEMBL4322069 0.84 CYP2A6 (0.70) CYP2A6CYP1A2MAOBTDP1ALDH1A1
SCHEMBL23555855 0.84 CYP1A2 (0.72) CYP2A6CYP1A2TDP1ALDH1A1KDM4E
SCHEMBL19287326 0.81 CYP1A2 (0.68) CYP2A6CYP1A2MAOBTDP1ALDH1A1
SCHEMBL9187014 0.81 CYP1A2 (0.68) CYP2A6CYP1A2MAOBTDP1ALDH1A1
SCHEMBL4659246 0.81 CYP11B1 (0.57) CYP2A6CYP11B1CYP11B2ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017204556-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME AND ELECTRONIC DEVICE THEREFOR 덕산네오룩스 주식회사 2017-11-30 WO disclosed