SCHEMBL1966100

SCHEMBL1966100

CC(C)(C)OC(=O)N1CCC2(CC1)CC2(Cl)Cl

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HPGD P15428 1/20 0.43
EPHX2 P34913 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
RECQL P46063 1/20 0.41
EPHX1 P07099 1/20 0.41
DDB1 Q16531 1/20 0.40
CRBN Q96SW2 1/20 0.40
TSHR P16473 2/20 0.39
ALOX15 P16050 1/20 0.39
ATM Q13315 1/20 0.39
POLB P06746 1/20 0.39
OPRD1 P41143 1/20 0.39
OPRK1 P41145 1/20 0.39
GPR119 Q8TDV5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16635353 0.83 USP2 (0.50) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL23875093 0.83 USP2 (0.50) USP2SMN1; SMN2HPGDEPHX2MEN1
SCHEMBL24145961 0.80 USP2 (0.47) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL3240640 0.80 USP2 (0.44) USP2SMN1; SMN2HPGDEPHX2MEN1
SCHEMBL25678641 0.79 USP2 (0.43) USP2SMN1; SMN2HPGDEPHX2MEN1
SCHEMBL3436829 0.78 USP2 (0.56) USP2SMN1; SMN2HPGDEPHX2MEN1
SCHEMBL346995 0.78 USP2 (0.56) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL23797358 0.78 USP2 (0.45) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL30396068 0.77 USP2 (0.44) USP2SMN1; SMN2HPGDEPHX2
SCHEMBL30825786 0.77 USP2 (0.44) USP2SMN1; SMN2HPGDEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102137841-B Ortho-substituted haloalkylsulfonanilide derivative and herbicide NISSAN CHEMICAL IND LTD 2014-05-14 CN disclosed
EP-2336104-A1 ORTHO-SUBSTITUTED HALOALKYLSULFONANILIDE DERIVATIVE AND HERBICIDE Nissan Chemical Industries, Ltd. (JP) 2011-06-22 EP disclosed