Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20996056 | 0.90 | EGFR (0.33) | — | |
| SCHEMBL19661033 | 0.81 | GRM2 (0.35) | TLR7 | |
| SCHEMBL19661204 | 0.81 | CSNK2A1 (0.37) | CSNK2A1 | |
| SCHEMBL20261964 | 0.81 | TLR7 (0.35) | TLR7 | |
| SCHEMBL2747871 | 0.78 | FGFR1 (0.41) | NUDT1BACE1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL16484167 | 0.78 | GRIN2B (0.36) | TLR7 | |
| SCHEMBL18359327 | 0.77 | CYP19A1 (0.33) | TLR7 | |
| SCHEMBL24476360 | 0.76 | KAT2B (0.42) | TLR7 | |
| SCHEMBL29101651 | 0.76 | GLA (0.32) | — | |
| SCHEMBL1716185 | 0.73 | TLR7 (0.46) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205762-A1 | INHIBITORS OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE | PHARMACYCLICS LLC (US) | 2017-11-30 | — | — | WO | disclosed |