Sulfuric Acid

Sulfuric Acid

SCHEMBL1966148

Nc1ncnc(N)c1N.O=S(=O)(O)O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NTRK1 known ✓ P04629 1/20 0.31
MAP2K2 known ✓ P36507 1/20 0.31
MAP2K1 known ✓ Q02750 1/20 0.31
NTRK3 known ✓ Q16288 1/20 0.31
NTRK2 known ✓ Q16620 1/20 0.31
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
NFKB1 P19838 1/20 0.36
THPO P40225 1/20 0.36
BLM P54132 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
KDM4E B2RXH2 3/20 0.35
GAA P10253 3/20 0.35
MEN1 O00255 2/20 0.35
MAPT P10636 2/20 0.35
RAB9A P51151 2/20 0.35
KMT2A Q03164 2/20 0.35
PKM P14618 1/20 0.35
LRRK2 Q5S007 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL4798019 0.97 CYP1A2 (0.35) CYP1A2CYP3A4NFKB1THPOBLM
Sulfuric Acid SCHEMBL3253536 0.86 CYP1A2 (0.33) CYP1A2CYP3A4NFKB1THPOBLM
Sulfuric Acid SCHEMBL31206216 0.86 CYP1A2 (0.33) CYP1A2CYP3A4NFKB1THPOBLM
Hydrochloric Acid SCHEMBL28174894 0.80 PI4KA (0.42) KDM4EGAALRRK2RETCHEK1
Sulfuric Acid SCHEMBL10962909 0.75 PRMT1 (0.35) CYP1A2CYP3A4NFKB1THPOBLM
Sulfuric Acid SCHEMBL28904638 0.73 MEN1 (0.39) CYP3A4KDM4EGAAMEN1MAPT
Sulfuric Acid SCHEMBL6474843 0.72 CDK1 (0.42) CYP1A2CYP3A4NFKB1THPOBLM
Sulfuric Acid SCHEMBL31415093 0.72 CDK1 (0.42) CYP1A2CYP3A4NFKB1THPOBLM
Sulfuric Acid SCHEMBL8028117 0.72 MEN1 (0.38) CYP1A2CYP3A4TDP1KDM4EGAA
Adenine SCHEMBL27690901 0.71 PI4KA (0.40) CYP1A2CYP3A4NFKB1THPOBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170328837-A1 SERS-BASED ANALYTE DETECTION AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-11-16 US claimed
US-9689801-B2 SERS-based analyte detection AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-06-27 US claimed
EP-2516995-B1 SERS-BASED ANALYTE DETECTION AGENCY SCIENCE TECH & RES (SG) 2016-10-26 EP claimed
CN-102812348-B Analysis quality testing based on SERS is surveyed AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2016-02-03 CN claimed
US-20130023435-A1 SERS-BASED ANALYTE DETECTION AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2013-01-24 US claimed
EP-2516995-A1 SERS-BASED ANALYTE DETECTION Agency For Science, Technology And Research (SG) 2012-10-31 EP claimed
WO-2011078794-A1 SERS-BASED ANALYTE DETECTION AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-30 WO claimed
US-20250327028-A1 ENGINEERED PLATELETS AS TARGETED PROTEIN DEGRADERS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2025-10-23 US disclosed
US-12054768-B2 Methods for detecting agglutination and compositions for use in practicing the same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-08-06 US disclosed
US-20240094187-A1 SURFACE ENHANCED RAMAN SPECTROSCOPIC METHODS FOR DETECTING ANALYTES BECKMAN COULTER, INC. (US) 2024-03-21 US disclosed
CN-117120828-A Surface enhanced Raman spectroscopy for detection of analytes 贝克曼库尔特有限公司 2023-11-24 CN disclosed
EP-4271984-A1 SURFACE ENHANCED RAMAN SPECTROSCOPIC METHODS FOR DETECTING ANALYTES Beckman Coulter, Inc. (US) 2023-11-08 EP disclosed
EP-4123031-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME The Regents of The University of California (US) 2023-01-25 EP disclosed
WO-1993006522-A1 PROCESS FOR THE PREPARATION OF HIGH CHLORIDE TABULAR GRAIN EMULSIONS (IV) EASTMAN KODAK COMPANY (US) 1993-04-01 WO disclosed
EP-0534323-A1 Process for the preparation of high chloride tabular grain emulsions (II) EASTMAN KODAK COMPANY (US) 1993-03-31 EP disclosed
US-5185239-A Triaminopyridine grain growth modifier EASTMAN KODAK COMPANY (US) 1993-02-09 US disclosed
US-5178997-A A fused N-heterocyclic compound as a grain growth modifier; materials handling EASTMAN KODAK COMPANY (US) 1993-01-12 US disclosed
US-5047405-A Alzheimer*s disease BIORESEARCH S.P.A. (IT) 1991-09-10 US disclosed
EP-0290819-A2 Pteridines suitable for the preparation of pharmaceutical compositions with antiamnesic activity BIORESEARCH S.p.A. (IT) 1988-11-17 EP disclosed
US-4187307-A 4-AMINOPTERIDINES ABBOTT LABORATORIES (US) 1980-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250327028-A1 ENGINEERED PLATELETS AS TARGETED PROTEIN DEGRADERS HSP90B1, HSP90AB1, HSP90AA1 NTRK1 2983/4885MAP2K2 2888/4885MAP2K1 3349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.