Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.75 |
| ▸ | POLA1 | P09884 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19662708 | 1.00 | KDM4E (0.75) | KDM4EPOLA1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL21787191 | 0.91 | KDM4E (0.62) | KDM4EPOLA1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL21538044 | 0.88 | KDM4E (0.81) | KDM4EPOLA1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL22315215 | 0.86 | KDM4E (0.74) | KDM4EPOLA1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL9703289 | 0.86 | KDM4E (0.74) | KDM4EPOLA1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL30057780 | 0.85 | KDM4E (1.00) | KDM4EPOLA1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL23225351 | 0.85 | KDM4E (0.77) | KDM4EPOLA1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL24822974 | 0.85 | KDM4E (0.62) | KDM4EPOLA1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL21538041 | 0.84 | KDM4E (0.75) | KDM4EPOLA1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL18671307 | 0.83 | KDM4E (0.63) | KDM4EPOLA1TAS1R3TAS1R1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205336-A1 | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-11-30 | — | — | WO | disclosed |