SCHEMBL30057780

SCHEMBL30057780

C#CCO[C@@H]1C[C@H](n2cnc3c(=O)[nH]c(NC(=O)C(C)C)nc32)O[C@@H]1CO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 1.00
▸ POLA1 P09884 1/20 0.47
▸ TAS1R3 Q7RTX0 1/20 0.43
▸ TAS1R1 Q7RTX1 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.39
▸ HPGD P15428 1/20 0.37
▸ POLB P06746 1/20 0.37
▸ MEN1 O00255 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ HIF1A Q16665 1/20 0.35
▸ RNASE1 P07998 1/20 0.35
▸ P2RY1 P47900 1/20 0.35
▸ PNP P00491 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ TP53 P04637 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ PDE4D Q08499 1/20 0.35
▸ PDE3A Q14432 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ RXFP1 Q9HBX9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21538044 0.90 KDM4E (0.81) KDM4EPOLA1TAS1R3TAS1R1ALDH1A1
SCHEMBL19035574 0.89 KDM4E (0.79) KDM4EPOLA1TAS1R3TAS1R1HPGD
SCHEMBL23225351 0.87 KDM4E (0.77) KDM4EPOLA1TAS1R3TAS1R1ALDH1A1
SCHEMBL19662708 0.85 KDM4E (0.75) KDM4EPOLA1TAS1R3TAS1R1ALDH1A1
SCHEMBL21538041 0.85 KDM4E (0.75) KDM4EPOLA1TAS1R3TAS1R1ALDH1A1
SCHEMBL19662704 0.85 KDM4E (0.75) KDM4EPOLA1TAS1R3TAS1R1ALDH1A1
SCHEMBL22315215 0.85 KDM4E (0.74) KDM4EPOLA1TAS1R3TAS1R1ALDH1A1
SCHEMBL9703289 0.85 KDM4E (0.74) KDM4EPOLA1TAS1R3TAS1R1ALDH1A1
SCHEMBL18166264 0.85 KDM4E (0.74) KDM4EPOLA1TAS1R3TAS1R1ALDH1A1
SCHEMBL16568124 0.84 KDM4E (0.73) KDM4EPOLA1TAS1R3TAS1R1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260043172-A1 METHODS AND SYSTEMS FOR GENERATING NUCLEIC ACID DIVERSITY IN CRISPR-ASSOCIATED GENES PASTEUR INSTITUT (FR) 2026-02-12 — — US disclosed
EP-4522754-A1 SYNTHETIC SELF-AMPLIFYING MRNA MOLECULES WITH SECRETION ANTIGEN AND IMMUNOMODULATOR Sunvax MRNA Therapeutics Inc. (US) 2025-03-19 — — EP disclosed
EP-4517451-A1 INFORMATION PROCESSING APPARATUS, INFORMATION PROCESSING METHOD, AND INFORMATION PROCESSING PROGRAM Yokogawa Electric Corporation (JP) 2025-03-05 — — EP disclosed
US-20250068437-A1 INFORMATION PROCESSING APPARATUS, INFORMATION PROCESSING METHOD, AND COMPUTER-READABLE RECORDING MEDIUM YOKOGAWA ELECTRIC CORPORATION (JP) 2025-02-27 — — US disclosed
CN-119512622-A Information processing apparatus, information processing method, and computer-readable recording medium 横河电机株式会社 2025-02-25 — — CN disclosed
WO-2025010420-A2 COMPOSITIONS AND METHODS FOR DELIVERING MOLECULES SunVax mRNA Therapeutics Inc. (US) 2025-01-09 — — WO disclosed
US-20240182886-A1 METHODS AND SYSTEMS FOR GENERATING NUCLEIC ACID DIVERSITY INSTITUT PASTEUR (FR) 2024-06-06 — — US disclosed
WO-2023220693-A1 SYNTHETIC SELF-AMPLIFYING MRNA MOLECULES WITH SECRETION ANTIGEN AND IMMUNOMODULATOR SunVax mRNA Therapeutics Inc. (US) 2023-11-16 — — WO disclosed
EP-3412765-B1 METHOD FOR PRODUCING MUTANT FILAMENTOUS FUNGI KAO CORP (JP) 2023-01-18 — — EP disclosed
CN-115239477-A Interest calculation method and device 中国银行股份有限公司 2022-10-25 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260043172-A1 METHODS AND SYSTEMS FOR GENERATING NUCLEIC ACID DIVERSITY IN CRISPR-ASSOCIATED GENES MUS81, DHX9, POLR1E KDM4E 1595/4885POLA1 108/4885TAS1R3 3023/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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