Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19655507 | 0.85 | ANPEP (0.41) | — | |
| SCHEMBL20997389 | 0.83 | MEN1 (0.34) | CYP2C19KMT2ACYP2D6CYP2C9TSHR | |
| SCHEMBL23945860 | 0.79 | GBA1 (0.45) | RECQL | |
| SCHEMBL26501075 | 0.79 | CYP19A1 (0.33) | KMT2ACYP19A1MEN1NR2F2RAB9A | |
| SCHEMBL17324236 | 0.77 | CYP19A1 (0.38) | KMT2ACYP19A1MEN1 | |
| SCHEMBL24233268 | 0.76 | CYP19A1 (0.40) | CYP19A1 | |
| SCHEMBL26011534 | 0.76 | KMT2A (0.39) | KMT2AGAACYP19A1MEN1 | |
| SCHEMBL20073431 | 0.76 | ALDH1A1 (0.39) | KMT2ATSHRMEN1NR2F2RAB9A | |
| SCHEMBL22790888 | 0.76 | GBA1 (0.43) | RECQLCYP2C19KMT2ACYP2D6CYP2C9 | |
| SCHEMBL14434944 | 0.75 | CYP19A1 (0.42) | CYP19A1MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159554-A1 | COMPOUND WITH ANTICANCER ACTIVITY | KYOWA KIRIN CO., LTD. (JP) | 2023-05-25 | — | — | US | disclosed |
| US-11241502-B2 | Stable compositions of pegylated carfilzomib compounds | AMGEN INC. (US) | 2022-02-08 | — | — | US | disclosed |
| US-20190142957-A1 | STABLE COMPOSITIONS OF PEGYLATED CARFILZOMIB COMPOUNDS | AMGEN INC. | 2019-05-16 | — | — | US | disclosed |
| US-20170340746-A1 | PEGYLATED CARFILZOMIB COMPOUNDS | AMGEN INC. | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170340746-A1 | PEGYLATED CARFILZOMIB COMPOUNDS | MCL1, FCGRT, MAN2B1 | RECQL 3256/4885CYP2C19 1839/4885KMT2A 745/4885 |
| US-20190142957-A1 | STABLE COMPOSITIONS OF PEGYLATED CARFILZOMIB COMPOUNDS | MCL1, PHOSPHO1, PSMB5 | RECQL 3313/4885CYP2C19 634/4885KMT2A 775/4885 |
| US-20230159554-A1 | COMPOUND WITH ANTICANCER ACTIVITY | TP53, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, RCC2 | RECQL 2668/4885CYP2C19 2991/4885KMT2A 2349/4885 |
| US-11241502-B2 | Stable compositions of pegylated carfilzomib compounds | MCL1, PHOSPHO1, PSMB5 | RECQL 3313/4885CYP2C19 634/4885KMT2A 775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.