Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12670825 | 0.85 | CA12 (0.56) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL20994146 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL18761547 | 0.81 | MAPT (0.70) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13845095 | 0.79 | GRM2 (0.54) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL22612150 | 0.79 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9305839 | 0.79 | MC5R (0.58) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL12031409 | 0.76 | ALDH1A1 (0.69) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL15459228 | 0.76 | ALDH1A1 (0.75) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL23378222 | 0.76 | KDM4E (0.46) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL6484144 | 0.75 | HDAC8 (0.47) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489390-A1 | ELECTROCHEMICAL METHOD FOR O-C COUPLING OF UNPROTECTED PHENOLS WITH OPTICALLY PURE ARYLAMINES | Evonik Degussa GmbH (DE) | 2019-05-29 | — | — | EP | disclosed |
| EP-3252033-B1 | TWO-STAGE SYNTHESIS OF N BIARYL COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2018-06-27 | — | — | EP | disclosed |
| EP-3252033-A1 | TWO-STAGE SYNTHESIS OF N BIARYL COMPOUNDS | Evonik Degussa GmbH (DE) | 2017-12-06 | — | — | EP | disclosed |