⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28381910 | 0.95 | — | — | |
| SCHEMBL19462711 | 0.95 | — | — | |
| SCHEMBL27189112 | 0.84 | — | — | |
| SCHEMBL20582581 | 0.78 | KCNMA1 (0.31) | — | |
| SCHEMBL19873364 | 0.77 | — | — | |
| SCHEMBL29544944 | 0.75 | SIRT2 (0.49) | — | |
| SCHEMBL118552 | 0.75 | SIRT2 (0.49) | — | |
| Fluoride Ion SCHEMBL4594160 | 0.74 | SIRT2 (0.48) | — | |
| Bromide SCHEMBL5514450 | 0.74 | SIRT2 (0.48) | — | |
| SCHEMBL30056078 | 0.74 | SIRT2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3067351-B1 | COMPOUND HAVING HIGHER INHIBITION OF PROTEIN KINASE G ACTIVITY AND PREPARATION METHOD THEREFOR | JENKEM TECH CO LTD TIANJIN (CN) | 2019-02-06 | — | — | EP | claimed |
| US-20240092774-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2024-03-21 | — | — | US | disclosed |
| US-20190010204-A1 | METHOD FOR PREPARING SERMAGLUTIDE | Hybio Pharmaceutical Co., Ltd. (CN) | 2019-01-10 | — | — | US | disclosed |
| EP-3251698-A1 | LIGAND-CYTOTOXICITY DRUG CONJUGATE, PREPARING METHOD THEREFOR, AND APPLICATION THEREOF | Jiangsu Hengrui Medicine Co. Ltd. (CN) | 2017-12-06 | — | — | EP | disclosed |