Bicarbonate

Bicarbonate

SCHEMBL19664200

O=C(O)O.[H+].[H+].[NaH].[NaH]

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL22558174 1.00
Bicarbonate SCHEMBL19667921 1.00
Bicarbonate SCHEMBL11077238 1.00
Bicarbonate SCHEMBL4310468 1.00
Bicarbonate SCHEMBL28159606 0.94 CA1 (0.62)
Bicarbonate SCHEMBL28291177 0.94
Bicarbonate SCHEMBL23174995 0.93
Bicarbonate SCHEMBL10386542 0.93 CA1 (0.83)
Bicarbonate SCHEMBL294626 0.93 CA1 (0.83)
Bicarbonate SCHEMBL21796220 0.93 CA1 (0.83)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3252041-B1 BIPYRIDINE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL SUMITOMO CHEMICAL CO (JP) 2020-03-04 EP disclosed
US-10173997-B2 Bipyridine compound and use of same for noxious arthropod control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-01-08 US disclosed
US-20180009778-A1 BIPYRIDINE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-11 US disclosed
EP-3252041-A1 BIPYRIDINE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL Sumitomo Chemical Company, Limited (JP) 2017-12-06 EP disclosed