Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.83 |
| ▸ | CA2 | P00918 | 1/20 | 0.83 |
| ▸ | CA9 | Q16790 | 1/20 | 0.83 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | LDHA | P00338 | 2/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL308226 | 1.00 | — | — | |
| Bicarbonate SCHEMBL7705691 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL87276 | 1.00 | — | — | |
| Bicarbonate SCHEMBL10386542 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL10904150 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL3995099 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL5836395 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL8000370 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL21796220 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL8209384 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11597694-B2 | Method for producing lactic acid and method for producing polylactic acid | TORAY INDUSTRIES, INC. (JP) | 2023-03-07 | — | — | US | disclosed |
| CN-110388199-B | Large-discharge-capacity composite acid fracturing modification method for carbonate reservoir | 中国石油天然气股份有限公司 | 2021-06-01 | — | — | CN | disclosed |
| US-20200325097-A1 | METHOD FOR PRODUCING LACTIC ACID AND METHOD FOR PRODUCING POLYLACTIC ACID | TORAY INDUSTRIES, INC. (JP) | 2020-10-15 | — | — | US | disclosed |
| EP-2175029-B1 | LACTIC ACID PRODUCTION METHOD | TORAY INDUSTRIES (JP) | 2020-10-07 | — | — | EP | disclosed |
| US-10683254-B2 | Method for producing lactic acid and method for producing polylactic acid | TORAY INDUSTRIES, INC. (JP) | 2020-06-16 | — | — | US | disclosed |
| US-10584084-B2 | Process for producing 2,3-butanediol | TORAY INDUSTRIES, INC. (JP) | 2020-03-10 | — | — | US | disclosed |
| EP-3147275-B1 | METHOD FOR PRODUCING LACTIC ACID AND METHOD FOR PRODUCING POLYLACTIC ACID | TORAY INDUSTRIES (JP) | 2019-10-23 | — | — | EP | disclosed |
| EP-2551254-B1 | BUTANOL MANUFACTURING METHOD | TORAY INDUSTRIES (JP) | 2018-11-14 | — | — | EP | disclosed |
| EP-2767589-B1 | PROCESS FOR PRODUCING 2,3-BUTANEDIOL | TORAY INDUSTRIES (JP) | 2017-12-20 | — | — | EP | disclosed |
| EP-3147275-A1 | METHOD FOR PRODUCING LACTIC ACID AND METHOD FOR PRODUCING POLYLACTIC ACID | TORAY INDUSTRIES, INC. (JP) | 2017-03-29 | — | — | EP | disclosed |
| EP-1141697-A1 | CURRENT-EFFICIENT SUPPRESSORS AND METHOD OF USE | DIONEX CORPORATION (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2001067091-A1 | METHOD AND APPARATUS FOR GAS-ASSISTED SUPPRESSED CHROMATOGRAPHY | DIONEX CORPORATION (US) | 2001-09-13 | — | — | WO | disclosed |
| WO-2000042426-A9 | CURRENT-EFFICIENT SUPPRESSORS AND METHOD OF USE | DIONEX CORP (US) | 2001-09-07 | — | — | WO | disclosed |
| WO-2000042426-A1 | CURRENT-EFFICIENT SUPPRESSORS AND METHOD OF USE | DIONEX CORPORATION (US) | 2000-07-20 | — | — | WO | disclosed |
| US-6086847-A | Process for treating iron-containing sulfide rocks and ores | UNIVERSITY OF NEVADA (US) | 2000-07-11 | — | — | US | disclosed |
| US-6077434-A | CURRENT-EFFICIENT DEVICE AND METHOD FOR REDUCING THE CONCENTRATION OF MATRIX IONS OF OPPOSITE CHARGE TO IONS TO BE ANALYZED, AND SPECIFICALLY FOR USE OF AN ION CHROMATOGRAPHY SUPPRESSOR OR TO A PRETREATMENT DEVICE | DIONEX CORPORATION (US) | 2000-06-20 | — | — | US | disclosed |
| EP-0871869-A4 | INTERMITTENT ELECTROLYTIC MEMBRANE SUPPRESSOR REGENERATION FOR ION CHROMATOGRAPHY | DIONEX CORP (US) | 1999-02-24 | — | — | EP | disclosed |
| EP-0871869-A2 | INTERMITTENT ELECTROLYTIC MEMBRANE SUPPRESSOR REGENERATION FOR ION CHROMATOGRAPHY | DIONEX CORPORATION (US) | 1998-10-21 | — | — | EP | disclosed |
| US-5569365-A | Intermittent electrolytic membrane suppressor regeneration for ion chromatography | DIONEX CORPORATION (US) | 1996-10-29 | — | — | US | disclosed |
| WO-1996028009-A2 | INTERMITTENT ELECTROLYTIC MEMBRANE SUPPRESSOR REGENERATION FOR ION CHROMATOGRAPHY | DIONEX CORPORATION (US) | 1996-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11597694-B2 | Method for producing lactic acid and method for producing polylactic acid | MLEC, FIBP, LDHA | CA1 312/4885CA2 86/4885CA9 27/4885 |
| US-10683254-B2 | Method for producing lactic acid and method for producing polylactic acid | MLEC, FIBP, LDHA | CA1 312/4885CA2 86/4885CA9 27/4885 |
| US-20200325097-A1 | METHOD FOR PRODUCING LACTIC ACID AND METHOD FOR PRODUCING POLYLACTIC ACID | MLEC, FIBP, LDHA | CA1 312/4885CA2 86/4885CA9 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.