⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL971354 | 0.67 | — | — | |
| SCHEMBL761617 | 0.67 | — | — | |
| SCHEMBL667084 | 0.67 | — | — | |
| SCHEMBL16320462 | 0.67 | — | — | |
| SCHEMBL156559 | 0.67 | — | — | |
| SCHEMBL9380203 | 0.67 | — | — | |
| SCHEMBL3144398 | 0.67 | — | — | |
| SCHEMBL371880 | 0.67 | — | — | |
| SCHEMBL9380211 | 0.67 | — | — | |
| SCHEMBL3143589 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112370462-A | Methods and compositions for treating COPD diseases | 上海凯屹医药科技有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-106456657-B | Methods and compositions for treating COPD diseases | 上海凯屹医药科技有限公司 | 2020-10-16 | — | — | CN | disclosed |
| EP-3252038-B1 | N-BENZOATE GROUP SUBSTITUTED BENZOPYRROLINE-2-ONE DERIVATIVE AND USE THEREOF | BEIJING HANMI PHARMACEUTICAL CO LTD (CN) | 2020-04-08 | — | — | EP | disclosed |
| US-10322108-B2 | N-benzoate group substituted benzopyrroline-2-one derivative and use thereof | Beijing Hanmi Pharmaceutical Co., Ltd. (CN) | 2019-06-18 | — | — | US | disclosed |
| US-20170368028-A1 | N-BENZOATE GROUP SUBSTITUTED BENZOPYRROLINE-2-ONE DERIVATIVE AND USE THEREOF | Beijing Hanmi Pharmaceutical Co., Ltd. (CN) | 2017-12-28 | — | — | US | disclosed |
| EP-3252038-A1 | N-BENZOATE GROUP SUBSTITUTED BENZOPYRROLINE-2-ONE DERIVATIVE AND USE THEREOF | Beijing Hanmi Pharmaceutical Co., Ltd. (CN) | 2017-12-06 | — | — | EP | disclosed |