⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL371880 | 1.00 | — | — | |
| SCHEMBL156559 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL9734775 | 0.97 | — | — | |
| Benzene SCHEMBL29043008 | 0.93 | TSHR (0.33) | — | |
| SCHEMBL439634 | 0.84 | — | — | |
| Biphenyl SCHEMBL27962710 | 0.83 | KMT2A (0.37) | — | |
| Pyrimidine SCHEMBL28223061 | 0.82 | — | — | |
| Pyridine SCHEMBL28106507 | 0.82 | TSHR (0.33) | — | |
| SCHEMBL734143 | 0.76 | — | — | |
| Ammonia Solution, Strong SCHEMBL11522067 | 0.76 | CA1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172222-A1 | Oxazolidinones for the Treatment of Inflammatory Conditions of the Gastrointestinal Tract | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-07-14 | — | — | US | disclosed |
| US-20110003804-A1 | Oxazolidinones For the Treatment and/or Prophylaxis of Heart Failure | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-01-06 | — | — | US | disclosed |
| US-20100144728-A1 | Oxazolidinone For The Treatment And Prophylaxis Of Pulmonary Hypertension | BAYER SCHERING PHARMA AG (DE) | 2010-06-10 | — | — | US | disclosed |
| US-20100125059-A1 | 1-BIARYLAZETIDINONE DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2010-05-20 | — | — | US | disclosed |
| EP-2140866-A1 | Oxazolidinones for the treatment of inflammatory conditions of the gastrointestinal tract | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2138178-A1 | Oxazolidninones for the treatment fo chronic obstructive pulmonary disease (COPD) and/or asthma | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-12-30 | — | — | EP | disclosed |
| EP-2133347-A1 | 1-BIARYLAZETIDINONE DERIVATIVES | Teijin Pharma Limited (JP) | 2009-12-16 | — | — | EP | disclosed |