SCHEMBL19664978

SCHEMBL19664978

COc1ccc(CCc2cnc3c(N)nc4c[c]ccc4c3c2)c(C)c1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1010175 0.86 TLR7 (0.68) TLR7
SCHEMBL1006099 0.85 TLR7 (0.76) TLR7
SCHEMBL1008418 0.83 TLR7 (0.77) TLR7
SCHEMBL1009605 0.83 TLR7 (0.77) TLR7
SCHEMBL18598573 0.81 TLR7 (0.75) TLR7
SCHEMBL1009182 0.81 TLR7 (0.77) TLR7
SCHEMBL1060029 0.80 TLR7 (0.74) TLR7
SCHEMBL1061173 0.80 TLR7 (0.77) TLR7
SCHEMBL12723160 0.80 TLR7 (0.81) TLR7
SCHEMBL255072 0.80 TLR7 (1.00) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2440245-B1 BENZONAPHTHYRIDINE-CONTAINING VACCINES GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2017-12-06 EP claimed