Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1062200 | 0.86 | TLR7 (0.55) | TLR7 | |
| SCHEMBL1059459 | 0.85 | TLR7 (0.45) | TLR7 | |
| SCHEMBL1062254 | 0.85 | TLR7 (0.54) | TLR7 | |
| SCHEMBL1064056 | 0.78 | TLR7 (0.59) | TLR7 | |
| SCHEMBL1059794 | 0.76 | TLR7 (0.53) | TLR7 | |
| SCHEMBL1010323 | 0.75 | TLR7 (0.53) | TLR7 | |
| SCHEMBL1061678 | 0.75 | TLR7 (0.56) | TLR7 | |
| SCHEMBL1007910 | 0.74 | TLR7 (0.60) | TLR7 | |
| SCHEMBL1008618 | 0.74 | TLR7 (0.60) | TLR7 | |
| SCHEMBL1062005 | 0.73 | ALDH1A1 (0.46) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440245-B1 | BENZONAPHTHYRIDINE-CONTAINING VACCINES | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2017-12-06 | — | — | EP | disclosed |