Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3623069 | 0.86 | TSHR (0.44) | TSHRGAASMN1; SMN2ADORA3KDM4E | |
| SCHEMBL10607021 | 0.85 | TSHR (0.43) | TSHRGAASMN1; SMN2ADORA3KDM4E | |
| SCHEMBL11453583 | 0.82 | HTT (0.41) | TSHRSMN1; SMN2ADORA3KDM4EMEN1 | |
| SCHEMBL10702538 | 0.79 | ALDH1A1 (0.47) | KMT2AALDH1A1 | |
| SCHEMBL5479510 | 0.76 | POLB (0.38) | TSHRSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL316145 | 0.76 | EDNRA (0.35) | CYP2C19OPRK1ALDH1A1 | |
| SCHEMBL21173936 | 0.76 | POLB (0.32) | GAASMN1; SMN2CYP2C19 | |
| SCHEMBL9488777 | 0.75 | PPARG (0.38) | TSHRGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL9487817 | 0.75 | PPARG (0.38) | TSHRGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL10766495 | 0.75 | SMN1; SMN2 (0.36) | TSHRGAASMN1; SMN2ADORA3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2510039-A1 | COPOLYETHER ESTER ELASTOMER | Invista Technologies S.à.r.l. (CH) | 2012-10-17 | — | — | EP | claimed |
| WO-2011071558-A1 | COPOLYETHER ESTER ELASTOMER | INVISTA TECHNOLOGIES S.A R.L. (CH) | 2011-06-16 | — | — | WO | claimed |