Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 4/20 | 0.63 |
| ▸ | HTR3A | P46098 | 2/20 | 0.63 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.45 |
| ▸ | GSK3B | P49841 | 4/20 | 0.45 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.43 |
| ▸ | WNT1 | P04628 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1967392 | 1.00 | CHRNA7 (0.63) | CHRNA7HTR3AUSP30DYRK1AGSK3B | |
| SCHEMBL1965653 | 1.00 | CHRNA7 (0.63) | CHRNA7HTR3AUSP30DYRK1AGSK3B | |
| SCHEMBL12339925 | 0.83 | CHRNA7 (0.74) | CHRNA7HTR3A | |
| SCHEMBL261083 | 0.83 | CHRNA7 (0.77) | CHRNA7HTR3ADYRK1AGSK3B | |
| SCHEMBL261646 | 0.83 | CHRNA7 (0.77) | CHRNA7HTR3ADYRK1AGSK3B | |
| SCHEMBL2454962 | 0.83 | CHRNA7 (0.77) | CHRNA7HTR3ADYRK1AGSK3B | |
| SCHEMBL1964372 | 0.82 | CHRNA7 (0.61) | CHRNA7HTR3AUSP30DYRK1AGSK3B | |
| SCHEMBL5994565 | 0.82 | CHRNA7 (0.61) | CHRNA7HTR3AUSP30DYRK1AGSK3B | |
| SCHEMBL1966893 | 0.82 | CHRNA7 (0.61) | CHRNA7HTR3AUSP30DYRK1AGSK3B | |
| SCHEMBL492328 | 0.82 | CHRNA7 (0.63) | CHRNA7HTR3AUSP30DYRK1AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336128-A1 | Benzoisothiazoles and preparation and uses thereof | Memory Pharmaceuticals Corporation (US) | 2011-06-22 | — | — | EP | disclosed |