Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 1/20 | 0.30 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL334311 | 0.75 | IDO1 (0.47) | IDO1QPCTQPCTL | |
| SCHEMBL400015 | 0.72 | IDO1 (0.32) | IDO1 | |
| SCHEMBL399396 | 0.66 | NUDT1 (0.48) | IDO1QPCTQPCTL | |
| SCHEMBL22281989 | 0.65 | JAK3 (0.47) | — | |
| SCHEMBL21672758 | 0.64 | TNKS (0.37) | IDO1QPCTQPCTL | |
| SCHEMBL17896045 | 0.63 | ADORA1 (0.39) | IDO1 | |
| SCHEMBL31586210 | 0.63 | IDO1 (0.44) | IDO1QPCTQPCTL | |
| SCHEMBL5492666 | 0.62 | GAA (0.35) | IDO1 | |
| SCHEMBL20299311 | 0.61 | SMPD3 (0.37) | IDO1 | |
| SCHEMBL26328071 | 0.60 | TNKS (0.32) | IDO1QPCTQPCTL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170349593-A1 | BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349593-A1 | BTK INHIBITORS | BTK, SYK, LYN | IDO1 1115/4885QPCT 1779/4885QPCTL 2930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.