SCHEMBL19668577

SCHEMBL19668577

COc1ccccc1COC(=O)NC(CC1CCCCC1)C(=O)NC(C=O)CC1CCNC1=O

nearest known ligand 0.65

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CTSL P07711 5/20 0.65
CTSB P07858 4/20 0.65
CTSS P25774 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19668579 1.00 CTSL (0.65) CTSLCTSBCTSS
SCHEMBL30205457 1.00 CTSL (0.65) CTSLCTSBCTSS
SCHEMBL19668581 1.00 CTSL (0.65) CTSLCTSBCTSS
SCHEMBL30205474 0.89 CTSL (0.65) CTSLCTSB
SCHEMBL30205648 0.89 CTSL (0.65) CTSLCTSB
SCHEMBL24961102 0.87 CTSL (0.81) CTSLCTSB
SCHEMBL30205459 0.84 CTSL (0.68) CTSLCTSB
SCHEMBL25766766 0.82 CTSL (0.69) CTSLCTSB
SCHEMBL30205460 0.82 CTSL (0.69) CTSLCTSB
SCHEMBL25766870 0.82 CTSL (0.73) CTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3464647-A1 METHODS FOR DETECTING NOROVIRUS Quest Diagnostics Investments LLC (US) 2019-04-10 EP disclosed
WO-2017210558-A1 METHODS FOR DETECTING NOROVIRUS QUEST DIAGNOSTICS INVESTMENTS LLC (US) 2017-12-07 WO disclosed