Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.56 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19668426 | 0.87 | KDM4E (0.59) | HSD17B10KDM4EHTTALDH1A1LMNA | |
| SCHEMBL19668784 | 0.87 | HSD17B10 (0.61) | HSD17B10DRD3KDM4EMEN1KMT2A | |
| SCHEMBL19668397 | 0.87 | KDM4E (0.61) | HSD17B10DRD3KDM4EMEN1KMT2A | |
| SCHEMBL19668814 | 0.86 | KDM4E (0.65) | HSD17B10DRD3KDM4EMEN1KMT2A | |
| SCHEMBL19668782 | 0.84 | DRD3 (0.59) | HSD17B10DRD3KDM4EMEN1KMT2A | |
| SCHEMBL19668783 | 0.80 | KDM4E (0.57) | HSD17B10KDM4EHTTALDH1A1LMNA | |
| SCHEMBL21074769 | 0.78 | HSD17B10 (0.69) | HSD17B10DRD3KDM4EMEN1KMT2A | |
| SCHEMBL22698592 | 0.78 | HSD17B10 (0.84) | HSD17B10DRD3KDM4EMEN1KMT2A | |
| SCHEMBL2739071 | 0.77 | DRD3 (0.77) | HSD17B10DRD3KDM4EMEN1KMT2A | |
| 4-N-Acetyl-1-Piperazinyl-Norfloxacin SCHEMBL11027379 | 0.77 | HSD17B10 (0.83) | HSD17B10DRD3KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624057-B2 | Bisphosphonate quinolone conjugates and uses thereof | BIOVINC, LLC (US) | 2026-05-12 | — | — | US | disclosed |
| US-20240182504-A1 | BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF | BIOVINC LLC (US) | 2024-06-06 | — | — | US | disclosed |
| US-11840549-B2 | Bisphosphonate quinolone conjugates and uses thereof | BIOVINC, LLC (US) | 2023-12-12 | — | — | US | disclosed |
| US-11840549-B2 | Bisphosphonate quinolone conjugates and uses thereof | BIOVINC, LLC (US) | 2023-12-12 | — | — | US | disclosed |
| US-11840549-B2 | Bisphosphonate quinolone conjugates and uses thereof | BIOVINC, LLC (US) | 2023-12-12 | — | — | US | disclosed |
| US-20210101920-A1 | BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-04-08 | — | — | US | disclosed |
| US-20210101920-A1 | BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-04-08 | — | — | US | disclosed |
| US-10865220-B2 | Bisphosphonate quinolone conjugates and uses thereof | BIOVINC, LLC (US) | 2020-12-15 | — | — | US | disclosed |
| US-10865220-B2 | Bisphosphonate quinolone conjugates and uses thereof | BIOVINC, LLC (US) | 2020-12-15 | — | — | US | disclosed |
| US-20190169214-A1 | BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF | BIOVINC LLC (US) | 2019-06-06 | — | — | US | disclosed |
| US-20190169214-A1 | BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF | BIOVINC LLC (US) | 2019-06-06 | — | — | US | disclosed |
| EP-3464307-A1 | BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF | Biovinc, LLC. (US) | 2019-04-10 | — | — | EP | disclosed |
| WO-2017210611-A1 | BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF | BIOVINC, LLC. (US) | 2017-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10865220-B2 | Bisphosphonate quinolone conjugates and uses thereof | BPGM, PHPT1, NQO2 | HSD17B10 2282/4885DRD3 2738/4885KDM4E 3437/4885 |
| US-20190169214-A1 | BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF | BPGM, PHPT1, NQO2 | HSD17B10 2282/4885DRD3 2738/4885KDM4E 3437/4885 |
| US-20240182504-A1 | BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF | BPGM, PHPT1, NQO2 | HSD17B10 2282/4885DRD3 2738/4885KDM4E 3437/4885 |
| US-11840549-B2 | Bisphosphonate quinolone conjugates and uses thereof | BPGM, PHPT1, NQO2 | HSD17B10 2282/4885DRD3 2738/4885KDM4E 3437/4885 |
| US-12624057-B2 | Bisphosphonate quinolone conjugates and uses thereof | PTMS, CYP24A1, PHPT1 | HSD17B10 2445/4885DRD3 2336/4885KDM4E 476/4885 |
| US-20210101920-A1 | BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF | BPGM, PHPT1, NQO2 | HSD17B10 2282/4885DRD3 2738/4885KDM4E 3437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.