Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MANBA | O00462 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5963774 | 0.75 | — | — | |
| SCHEMBL887333 | 0.71 | — | — | |
| SCHEMBL6436137 | 0.69 | — | — | |
| SCHEMBL14627981 | 0.63 | LMNA (0.47) | MANBALMNATHRBHIF1A | |
| SCHEMBL12929846 | 0.61 | MANBA (0.41) | MANBALMNATHRBHIF1A | |
| SCHEMBL17035731 | 0.61 | MANBA (0.41) | MANBALMNATHRBHIF1A | |
| SCHEMBL17035711 | 0.61 | MANBA (0.41) | MANBALMNATHRBHIF1A | |
| SCHEMBL2600088 | 0.61 | MANBA (0.41) | MANBALMNATHRBHIF1A | |
| SCHEMBL17035713 | 0.61 | MANBA (0.41) | MANBALMNATHRBHIF1A | |
| SCHEMBL12899721 | 0.61 | MANBA (0.41) | MANBALMNATHRBHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834791-B2 | CRISPR-related methods and compositions with governing gRNAS | EDITAS MEDICINE, INC. (US) | 2017-12-05 | — | — | US | disclosed |