SCHEMBL19668945

SCHEMBL19668945

c1ccc(N(c2ccc(-c3cc(-c4ccc(N(c5ccccc5)c5ccc(-c6ccc7c(c6)CC7)cc5)cc4)cc(-c4ccc(N(c5ccccc5)c5ccc(-c6ccc7c(c6)CC7)cc5)cc4)c3)cc2)c2ccc(-c3ccc4c(c3)CC4)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
MAPT P10636 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 2/20 0.39
KDM4E B2RXH2 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
CYP2D6 P10635 1/20 0.39
HSD17B3 P37058 2/20 0.39
CYP11B1 P15538 3/20 0.37
CYP11B2 P19099 3/20 0.37
HTR2C P28335 1/20 0.36
HTR2B P41595 1/20 0.36
TDP2 O95551 1/20 0.36
PARP10 Q53GL7 1/20 0.35
PARP11 Q9NR21 1/20 0.35
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24032036 0.93 CYP11B1 (0.37) ALDH1A1MAPTL3MBTL1CYP1A2CYP3A4
SCHEMBL26082840 0.91 HSD17B3 (0.38) ALDH1A1MAPTL3MBTL1CYP1A2CYP3A4
SCHEMBL26082937 0.90 HSD17B3 (0.40) ALDH1A1MAPTL3MBTL1CYP1A2CYP3A4
SCHEMBL13837284 0.89 CYP11B1 (0.42) CYP1A2CYP3A4CYP2C9CYP2C19HSD17B3
SCHEMBL29338832 0.88 CYP11B1 (0.50) ALDH1A1MAPTL3MBTL1CYP1A2CYP3A4
SCHEMBL29338833 0.88 CYP11B1 (0.50) ALDH1A1MAPTL3MBTL1CYP1A2CYP3A4
SCHEMBL26082913 0.86 CYP11B1 (0.40) ALDH1A1MAPTL3MBTL1CYP1A2CYP3A4
SCHEMBL13837208 0.85 HSD17B3 (0.39) HSD17B3CYP11B1CYP11B2HTR2CHTR2B
SCHEMBL13836984 0.85 HSD17B3 (0.39) HSD17B3CYP11B1CYP11B2HTR2CHTR2B
SCHEMBL13837263 0.85 HSD17B3 (0.39) HSD17B3CYP11B1CYP11B2HTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9837616-B2 Aromatic amine derivative, and organic electroluminescent element containing same IDEMITSU KOSAN CO., LTD. (JP) 2017-12-05 US disclosed
US-9837616-B2 Aromatic amine derivative, and organic electroluminescent element containing same IDEMITSU KOSAN CO., LTD. (JP) 2017-12-05 US disclosed