SCHEMBL13837263

SCHEMBL13837263

Cc1ccc(-c2cccc(-c3ccc(N(c4ccc(-c5cccc(-c6ccc(N(c7ccccc7)c7ccccc7)cc6)c5)cc4)c4cccc(-c5ccc6c(c5)CC6)c4)cc3)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B3 P37058 2/20 0.39
DHODH Q02127 1/20 0.35
FLT3 P36888 1/20 0.35
SRD5A1 P18405 1/20 0.34
KCNA1 Q09470 1/20 0.34
KCNAB1 Q14722 1/20 0.34
HTR2C P28335 2/20 0.33
HTR2B P41595 2/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
PTPN5 P54829 1/20 0.33
APP P05067 1/20 0.33
HSD17B1 P14061 1/20 0.33
HSD17B2 P37059 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP2 O95551 1/20 0.33
ADRB3 P13945 1/20 0.32
CHRM2 P08172 1/20 0.32
HTR1A P08908 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13836984 1.00 HSD17B3 (0.39) HSD17B3DHODHFLT3SRD5A1KCNA1
SCHEMBL13837208 1.00 HSD17B3 (0.39) HSD17B3DHODHFLT3SRD5A1KCNA1
SCHEMBL15481338 0.99 HSD17B3 (0.39) HSD17B3DHODHFLT3SRD5A1KCNA1
SCHEMBL12620154 0.99 HSD17B3 (0.39) HSD17B3DHODHFLT3SRD5A1KCNA1
SCHEMBL12619667 0.94 CYP11B1 (0.36) HSD17B3CYP11B1CYP11B2HSD17B1HSD17B2
SCHEMBL26082937 0.91 HSD17B3 (0.40) HSD17B3SRD5A1HTR2CHTR2BCYP11B1
SCHEMBL12900204 0.91 TRPM8 (0.36) HSD17B3APPMEN1KMT2A
SCHEMBL12619696 0.91 HSD17B3 (0.36) HSD17B3FLT3SRD5A1KCNA1KCNAB1
SCHEMBL12606451 0.90 KCNA1 (0.37) HSD17B3FLT3SRD5A1KCNA1KCNAB1
SCHEMBL12619691 0.89 HSD17B1 (0.34) HSD17B3KCNA1KCNAB1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120286653-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC EL DISPLAY DEVICE, AND ORGANIC EL ILLUMINATOR MITSUBISHI CHEMICAL CORPORATION (JP) 2012-11-15 US disclosed