Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 4/20 | 0.40 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | IDH2 | P48735 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19669054 | 1.00 | NAMPT (0.41) | NAMPTROCK2RORCPTPRBKDM4E | |
| SCHEMBL16250024 | 1.00 | NAMPT (0.41) | NAMPTROCK2RORCPTPRBKDM4E | |
| Hydrochloric Acid SCHEMBL17770586 | 0.97 | NAMPT (0.39) | NAMPTROCK2RORCPTPRBKDM4E | |
| SCHEMBL17618888 | 0.96 | NAMPT (0.42) | NAMPTROCK2RORCPTPRBCA2 | |
| SCHEMBL16249987 | 0.92 | KDM4E (0.41) | KDM4ECA2CA9GAAMAPT | |
| SCHEMBL16754369 | 0.91 | IDH2 (0.41) | KDM4ECA2CA9GAAMAPT | |
| SCHEMBL17618886 | 0.90 | CA2 (0.37) | RORCPTPRBKDM4ECA2CA9 | |
| SCHEMBL19365570 | 0.90 | CA2 (0.37) | RORCPTPRBKDM4ECA2CA9 | |
| Trifluoroacetic Acid SCHEMBL16238731 | 0.89 | KDM4E (0.40) | KDM4ECA2CA9GAAMAPT | |
| SCHEMBL17618885 | 0.89 | KDM4E (0.39) | KDM4ECA2CA9GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834558-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-12-05 | — | — | US | disclosed |