Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 3/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | LIPC | P11150 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | ITK | Q08881 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 2/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17624582 | 0.93 | SCD (0.35) | SCDDEGS1FGFR4LPLLIPC | |
| SCHEMBL19669073 | 0.90 | SCD (0.37) | SCDDEGS1FGFR4KCNH2HRH3 | |
| SCHEMBL17618391 | 0.86 | SCD (0.41) | SCDDEGS1NPY5RABL1 | |
| SCHEMBL17618519 | 0.85 | SCD (0.43) | SCDDEGS1NPY5RABL1GRM5 | |
| SCHEMBL17618376 | 0.84 | GRM5 (0.39) | SCDGRM5 | |
| SCHEMBL17618499 | 0.84 | GRM5 (0.39) | SCDGRM5 | |
| SCHEMBL17618541 | 0.84 | SCD (0.38) | SCDDEGS1FGFR4LPLLIPC | |
| SCHEMBL17618513 | 0.84 | HCRTR1 (0.42) | SCDABL1GRM5HCRTR1 | |
| SCHEMBL17618679 | 0.83 | SCD (0.38) | SCDDEGS1FGFR4LPLLIPC | |
| SCHEMBL17618548 | 0.83 | VCP (0.37) | SCDDEGS1FGFR4LPLLIPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834558-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-12-05 | — | — | US | disclosed |