Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | RAF1 | P04049 | 2/20 | 0.37 |
| ▸ | BRAF | P15056 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | PTGES | O14684 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16249968 | 0.96 | MGLL (0.39) | MGLLRAF1BRAFTRPV1EPHB4 | |
| SCHEMBL17618334 | 0.88 | TRPV1 (0.36) | RAF1BRAFTRPV1EPHB4MAPT | |
| SCHEMBL16237965 | 0.87 | KMT2A (0.37) | RAF1BRAFTRPV1MAPTMEN1 | |
| SCHEMBL17618335 | 0.86 | TRPV1 (0.39) | TRPV1EPHB4MAPTMEN1ALDH1A1 | |
| SCHEMBL19699106 | 0.86 | MGLL (0.43) | MGLLRAF1BRAFTRPV1RORC | |
| SCHEMBL16775772 | 0.84 | FYN (0.37) | RAF1BRAFTRPV1EPHB4PTGES | |
| SCHEMBL16249949 | 0.84 | FYN (0.34) | RAF1BRAFTRPV1EPHB4MAPT | |
| SCHEMBL19365249 | 0.84 | TRPV1 (0.37) | RAF1BRAFTRPV1EPHB4MAPT | |
| Trifluoroacetic Acid SCHEMBL16238443 | 0.84 | TRPV1 (0.34) | RAF1BRAFTRPV1EPHB4MAPT | |
| SCHEMBL16754701 | 0.83 | DCUN1D1 (0.37) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834558-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-12-05 | — | — | US | disclosed |