Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19670985 | 0.90 | KDM4E (0.36) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL15428184 | 0.79 | MAPT (0.33) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL15428148 | 0.72 | ALDH1A1 (0.40) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL15428081 | 0.71 | HPRT1 (0.34) | ALDH1A1MAPTHPGD | |
| SCHEMBL15428237 | 0.70 | MAPT (0.36) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL15427877 | 0.70 | KDM4E (0.38) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL15428212 | 0.68 | KDM4E (0.34) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL15427878 | 0.67 | KDM4E (0.33) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL15427828 | 0.67 | ALDH1A1 (0.47) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL15428293 | 0.67 | KDM4E (0.32) | KDM4EMEN1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9837622-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-12-05 | — | — | US | disclosed |