SCHEMBL19670682

SCHEMBL19670682

CC(C)Cc1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 3/20 0.45
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
MAPT P10636 1/20 0.45
CYP2C19 P33261 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
PTGS1 P23219 3/20 0.44
PTGS2 P35354 3/20 0.44
LMNA P02545 2/20 0.44
AKR1C3 P42330 2/20 0.44
CXCR1 P25024 2/20 0.44
CXCR2 P25025 2/20 0.44
ALOX5 P09917 2/20 0.44
HTR2A P28223 2/20 0.44
ALB P02768 1/20 0.44
ESR1 P03372 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8640297 0.94 SIGMAR1 (0.43) CYP2C9KDM4EALDH1A1CYP1A2CYP3A4
SCHEMBL22404374 0.91 PTGS1 (0.45) CYP2C9PTGS1PTGS2LMNAAKR1C3
SCHEMBL18072642 0.90 TAAR1 (0.46) CYP2C9PTGS1PTGS2LMNAAKR1C3
SCHEMBL15199693 0.90 TAAR1 (0.46) CYP2C9PTGS1PTGS2LMNAAKR1C3
SCHEMBL15199682 0.87 DHODH (0.42) CYP2C9CYP2D6PTGS1PTGS2LMNA
SCHEMBL24245862 0.85 TSHR (0.42) CYP2C9TDP1L3MBTL1PTGS1PTGS2
SCHEMBL12893262 0.83 PTGS1 (0.40) CYP2C9ALDH1A1CYP2C19PTGS1PTGS2
SCHEMBL1591678 0.82 ESR1 (0.48) CYP2C9KDM4EALDH1A1CYP1A2CYP3A4
SCHEMBL19135765 0.82 SIGMAR1 (0.44) CYP2D6ALOX5HTR2ATSHRSLC6A2
SCHEMBL12238173 0.82 DHODH (0.39) CYP2C9ALDH1A1CYP2D6L3MBTL1PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9837619-B2 Delayed fluorescence compound, and organic light emitting diode and display device using the same LG DISPLAY CO., LTD. (KR) 2017-12-05 US disclosed