Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 9/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15427913 | 0.86 | PRKDC (0.40) | PRKDCMTORPARP1KDM4ENPC1 | |
| SCHEMBL15427875 | 0.78 | PRKDC (0.41) | PRKDCMTORPARP1KDM4ENPC1 | |
| SCHEMBL12145448 | 0.77 | MAPT (0.43) | PRKDCMTORPARP1KDM4ENPC1 | |
| SCHEMBL15427869 | 0.76 | PRKDC (0.38) | PRKDCMTORPARP1KDM4ENPC1 | |
| SCHEMBL1369733 | 0.74 | KDM4E (0.46) | PRKDCMTORPARP1KDM4ENPC1 | |
| SCHEMBL15428181 | 0.73 | PRKDC (0.40) | PRKDCMTORPARP1KDM4ENPC1 | |
| SCHEMBL14127581 | 0.72 | PRKDC (0.42) | PRKDCMTORPARP1MAPTRAB9A | |
| SCHEMBL12145438 | 0.72 | IKBKB (0.51) | PRKDCPARP1KDM4ENPC1MAPT | |
| SCHEMBL12145459 | 0.72 | PRKDC (0.42) | PRKDCMTORPARP1KDM4EMAPT | |
| SCHEMBL12145440 | 0.72 | MAPT (0.47) | PRKDCMTORPARP1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9837622-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-12-05 | — | — | US | disclosed |