Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPRA | P18433 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
| ▸ | PTPRE | P23469 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15428158 | 0.83 | L3MBTL1 (0.43) | L3MBTL1CETPKDM4ERAB9ANPSR1 | |
| SCHEMBL15428010 | 0.83 | SRC (0.44) | ERN1L3MBTL1CETPKDM4EMEN1 | |
| SCHEMBL6094043 | 0.79 | TACR1 (0.42) | L3MBTL1CETPKDM4EMEN1KMT2A | |
| SCHEMBL14355952 | 0.78 | ERN1 (0.46) | ERN1L3MBTL1KDM4EMEN1RAB9A | |
| SCHEMBL15427825 | 0.77 | CETP (0.57) | L3MBTL1CETPKDM4EMEN1RAB9A | |
| SCHEMBL4177446 | 0.76 | PTPRC (0.64) | L3MBTL1CETPKDM4EMEN1RAB9A | |
| SCHEMBL3010925 | 0.76 | POLB (0.44) | L3MBTL1KDM4ERAB9AKMT2ANPSR1 | |
| SCHEMBL2209063 | 0.76 | CETP (0.44) | ERN1L3MBTL1CETPKDM4EMEN1 | |
| SCHEMBL30922573 | 0.76 | L3MBTL1 (0.46) | L3MBTL1CETPKDM4EMEN1RAB9A | |
| SCHEMBL28579201 | 0.75 | MAPT (0.49) | ERN1MEN1RAB9AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9837622-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-12-05 | — | — | US | disclosed |