⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15718024 | 0.76 | POLRMT (0.32) | — | |
| SCHEMBL25400732 | 0.68 | DOT1L (0.38) | — | |
| SCHEMBL24790992 | 0.66 | — | — | |
| SCHEMBL17106728 | 0.65 | DOT1L (0.33) | — | |
| SCHEMBL19779083 | 0.64 | POLRMT (0.35) | — | |
| SCHEMBL15718955 | 0.64 | PNP (0.46) | — | |
| Hydrochloric Acid SCHEMBL17162016 | 0.63 | PNP (0.46) | — | |
| SCHEMBL24149348 | 0.63 | TMPRSS2 (0.42) | — | |
| SCHEMBL24791068 | 0.63 | POLRMT (0.35) | — | |
| SCHEMBL23959951 | 0.62 | POLRMT (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3251674-A2 | ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES | BioCryst Pharmaceuticals, Inc. (US) | 2017-12-06 | — | — | EP | disclosed |