Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP8 | P40818 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12098528 | 0.96 | MEN1 (0.39) | USP8ALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL12098214 | 0.93 | USP8 (0.40) | USP8ALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL10100905 | 0.93 | MAPK10 (0.41) | MAPK10MKNK1MEN1KMT2AHSP90AA1 | |
| SCHEMBL25946455 | 0.90 | ATM (0.42) | ALDH1A1MAPK10MKNK1MEN1KMT2A | |
| SCHEMBL21481265 | 0.89 | KDM4E (0.46) | MAPK10MKNK1MEN1KMT2AHSP90AA1 | |
| SCHEMBL17349308 | 0.88 | KDM4E (0.49) | MAPK10MKNK1MEN1KMT2AHSP90AA1 | |
| SCHEMBL11987859 | 0.88 | MAPK10 (0.41) | CYP11B1CYP11B2MAPK10MKNK1MEN1 | |
| SCHEMBL15945614 | 0.87 | KDM4E (0.44) | ALDH1A1MAPK10MAOAMAOB | |
| SCHEMBL31122338 | 0.87 | ALDH1A1 (0.52) | ALDH1A1MAPK1NPC1RAB9ANFKB1 | |
| SCHEMBL30045167 | 0.87 | ALDH1A1 (0.52) | ALDH1A1MAPK1NPC1RAB9ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9755152-B2 | Compound having substituted anthracene ring structure and pyridoindole ring structure, and organic electroluminescent device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2017-09-05 | — | — | US | disclosed |
| EP-2336130-B1 | COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENCE DEVICE | HODOGAYA CHEMICAL CO LTD (JP) | 2017-06-28 | — | — | EP | disclosed |
| US-20150155496-A1 | COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO LTD (JP) | 2015-06-04 | — | — | US | disclosed |
| EP-2463287-B1 | COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENCE DEVICE | HODOGAYA CHEMICAL CO LTD (JP) | 2015-03-18 | — | — | EP | disclosed |
| US-8927119-B2 | Compound having substituted anthracene ring structure and pyridoindole ring structure, and organic electroluminescent device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2015-01-06 | — | — | US | disclosed |
| US-20130341604-A1 | COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENCE DEVICE | HODOGAYA CHEMICAL CO LTD (JP) | 2013-12-26 | — | — | US | disclosed |
| US-8586210-B2 | Compound having substituted anthracene ring structure and pyridoindole ring structure and organic electroluminescence device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2013-11-19 | — | — | US | disclosed |
| EP-2463287-A1 | COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENCE DEVICE | Hodogaya Chemical Co., Ltd. (JP) | 2012-06-13 | — | — | EP | disclosed |
| US-20120126220-A1 | COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-05-24 | — | — | US | disclosed |
| US-20110175079-A1 | COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENCE DEVICE | HODOGAYA CHEMICAL CO., LTD. (JP) | 2011-07-21 | — | — | US | disclosed |
| EP-2336130-A1 | COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENCE DEVICE | Hodogaya Chemical Co., Ltd. (JP) | 2011-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150155496-A1 | COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE | SLCO2B1, PNPO, SLCO2A1 | USP8 4257/4885ALDH1A1 633/4885MAPK1 592/4885 |
| US-20120126220-A1 | COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE | SLCO2B1, PNPO, SLCO2A1 | USP8 4257/4885ALDH1A1 633/4885MAPK1 592/4885 |
| US-20110175079-A1 | COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENCE DEVICE | SLCO2A1, SLCO2B1, SLCO4C1 | USP8 4604/4885ALDH1A1 275/4885MAPK1 270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.