Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19992532 | 0.85 | BACE1 (0.38) | SMN1; SMN2BACE1BACE2ALDH1A1USP2 | |
| SCHEMBL17992189 | 0.81 | KMT2A (0.41) | HTTKMT2ASMN1; SMN2BACE1BACE2 | |
| SCHEMBL17668770 | 0.81 | KMT2A (0.47) | HTTKMT2ASMN1; SMN2BACE1BACE2 | |
| SCHEMBL1974946 | 0.79 | P4HTM (0.52) | HTTKMT2ASMN1; SMN2BACE1BACE2 | |
| SCHEMBL15669996 | 0.79 | KMT2A (0.44) | HTTKMT2ASMN1; SMN2BACE1BACE2 | |
| SCHEMBL1973974 | 0.79 | KMT2A (0.48) | HTTKMT2ASMN1; SMN2BACE1BACE2 | |
| SCHEMBL18811649 | 0.75 | BACE1 (0.38) | HTTKMT2ASMN1; SMN2BACE1BACE2 | |
| SCHEMBL28883583 | 0.75 | ALDH1A1 (0.35) | ACACBALDH1A1NPSR1MAPTP4HTM | |
| SCHEMBL17992215 | 0.72 | BACE1 (0.39) | HTTKMT2ASMN1; SMN2BACE1BACE2 | |
| SCHEMBL28028511 | 0.71 | KMT2A (0.45) | HTTKMT2ASMN1; SMN2BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3252041-B1 | BIPYRIDINE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL | SUMITOMO CHEMICAL CO (JP) | 2020-03-04 | — | — | EP | disclosed |
| EP-3252041-A1 | BIPYRIDINE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL | Sumitomo Chemical Company, Limited (JP) | 2017-12-06 | — | — | EP | disclosed |