Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1964347 | 0.96 | NR1H4 (0.82) | NR1H4KCNH2 | |
| SCHEMBL1965630 | 0.94 | NR1H4 (0.82) | NR1H4KCNH2 | |
| SCHEMBL1967457 | 0.91 | NR1H4 (0.82) | NR1H4KCNH2 | |
| SCHEMBL1241346 | 0.90 | NR1H4 (1.00) | NR1H4KCNH2 | |
| SCHEMBL4522570 | 0.89 | NR1H4 (1.00) | NR1H4KCNH2 | |
| SCHEMBL1967324 | 0.88 | NR1H4 (0.81) | NR1H4KCNH2 | |
| SCHEMBL4758760 | 0.87 | NR1H4 (0.82) | NR1H4KCNH2 | |
| SCHEMBL1241332 | 0.86 | NR1H4 (1.00) | NR1H4KCNH2 | |
| SCHEMBL1967103 | 0.86 | NR1H4 (0.81) | NR1H4KCNH2 | |
| SCHEMBL4759419 | 0.86 | NR1H4 (0.63) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334681-A1 | 1,2,3,6-TETRAHYDROAZEPINO[4,5-B]INDOLE-5-CARBOXYLATE NUCLEAR RECEPTOR INHIBITORS | Wyeth LLC (US) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010036362-A1 | 1,2,3,6-TETRAHYDROAZEPINO[4,5-B]INDOLE-5-CARBOXYLATE NUCLEAR RECEPTOR INHIBITORS | WYETH (US) | 2010-04-01 | — | — | WO | disclosed |