Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2692838 | 0.87 | TSHR (0.49) | GFERTSHRMAOBMAOAF2 | |
| Hydrochloric Acid SCHEMBL27741070 | 0.85 | TSHR (0.47) | GFERTSHRMAOBMAOAF2 | |
| SCHEMBL24769268 | 0.83 | GAA (0.47) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL19674114 | 0.83 | GFER (0.46) | GFERTSHRMAOBMAOAF2 | |
| SCHEMBL16743937 | 0.82 | TSHR (0.66) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL13971409 | 0.82 | TSHR (0.66) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL6178883 | 0.82 | TSHR (0.66) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL15160672 | 0.82 | NPC1 (0.45) | GFERTSHRITGB1ITGA5ITGB3 | |
| SCHEMBL15134805 | 0.82 | NPC1 (0.45) | GFERTSHRITGB1ITGA5ITGB3 | |
| SCHEMBL1349169 | 0.82 | F2 (0.46) | GFERTSHRF2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2654802-B1 | CHELATE NANOEMULSION FOR MRI | GUERBET SA (FR) | 2017-12-06 | — | — | EP | disclosed |