Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | PPID | Q08752 | 2/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16314712 | 0.85 | TSHR (0.46) | TSHRADRB2ADRB1ADRB3TAS1R3 | |
| SCHEMBL14032207 | 0.85 | ESR1 (0.53) | TSHRADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL17590465 | 0.83 | TSHR (0.52) | TSHRADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL16314618 | 0.83 | L3MBTL1 (0.48) | TSHRALDH1A1 | |
| SCHEMBL17590264 | 0.83 | L3MBTL1 (0.48) | TSHRALDH1A1 | |
| SCHEMBL5019059 | 0.83 | ESR1 (0.46) | TSHRADRB2ADRB1ADRB3PPID | |
| SCHEMBL6574637 | 0.83 | TSHR (0.65) | TSHRALDH1A1NPC1RAB9A | |
| SCHEMBL22338892 | 0.83 | ESR1 (0.46) | TSHRADRB2ADRB1ADRB3PPID | |
| SCHEMBL121124 | 0.83 | TSHR (0.65) | TSHRALDH1A1NPC1RAB9A | |
| SCHEMBL19647373 | 0.83 | ESR1 (0.46) | TSHRADRB2ADRB1ADRB3PPID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2388247-B1 | Histone deacetylase inhibitors | UNIV TAIPEI MEDICAL (TW) | 2017-08-02 | — | — | EP | disclosed |
| US-8242282-B2 | Histone deacetylase inhibitors | TAIPEI MEDICAL UNIVERSITY (TW) | 2012-08-14 | — | — | US | disclosed |
| US-20110288133-A1 | HISTONE DEACETYLASE INHIBITORS | TAIPEI MEDICAL UNIVERSITY (TW) | 2011-11-24 | — | — | US | disclosed |
| EP-2388247-A2 | Histone deacetylase inhibitors | Taipei Medical University (TW) | 2011-11-23 | — | — | EP | disclosed |
| US-8039296-B2 | Organic thin film transistor array panel and manufacturing method thereof | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2011-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288133-A1 | HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC5, HDAC2 | F2 4730/4885F10 4026/4885PRSS1 307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.