Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19674652 | 0.82 | POLB (0.33) | POLBHCAR2 | |
| SCHEMBL18845125 | 0.78 | KMT2A (0.32) | — | |
| SCHEMBL1403825 | 0.72 | POLB (0.36) | POLBHCAR2 | |
| SCHEMBL30639795 | 0.68 | POLB (0.37) | POLBHCAR2 | |
| SCHEMBL26614753 | 0.68 | POLB (0.37) | POLBHCAR2 | |
| SCHEMBL15074479 | 0.68 | POLB (0.33) | POLBHCAR2 | |
| SCHEMBL21231620 | 0.66 | KDM4E (0.40) | POLBHCAR2 | |
| SCHEMBL19674732 | 0.64 | KDM4E (0.38) | POLBHCAR2 | |
| SCHEMBL23087851 | 0.63 | HTT (0.42) | POLBHCAR2 | |
| SCHEMBL25254715 | 0.63 | MAPT (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794600-B1 | 2,3-Dihydro-benzo[1,4]oxazine derivatives and related compounds as phosphoinositide-3 kinase (PI3K) inhibitors for the treatment of e.g. rheumatoid arthritis | NOVARTIS AG (CH) | 2017-12-06 | — | — | EP | disclosed |