Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.49 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.49 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.49 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.49 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14621608 | 0.86 | KMT2A (0.51) | POLBNR4A1RAB9AMAPTMEN1 | |
| SCHEMBL13489787 | 0.84 | KMT2A (0.46) | POLBNR4A1RAB9AMAPTMEN1 | |
| SCHEMBL13102519 | 0.83 | HPGD (0.62) | POLBRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL13489789 | 0.83 | KMT2A (0.49) | POLBNR4A1RAB9AMAPTMEN1 | |
| SCHEMBL13490046 | 0.83 | ALDH1A1 (0.51) | POLBRAB9AMAPTMEN1KMT2A | |
| SCHEMBL14622121 | 0.83 | POLB (0.46) | POLBNR4A1RAB9AMAPTMEN1 | |
| SCHEMBL27823199 | 0.83 | POLB (0.46) | POLBNR4A1RAB9AMAP4K4NPY5R | |
| SCHEMBL1356705 | 0.82 | MAP4K4 (0.48) | POLBNR4A1RAB9AMAP4K4NPY5R | |
| SCHEMBL2337206 | 0.82 | ALDH1A1 (0.60) | POLBMAP4K4NPY5RTNKSPARP1 | |
| SCHEMBL3686435 | 0.82 | KMT2A (0.61) | POLBRAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2840080-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF | FUJIFILM CORP (JP) | 2017-12-06 | — | — | EP | disclosed |