SCHEMBL19677

SCHEMBL19677

[CH]1Cc2ccccc2N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170456 0.75 PLAU (0.43)
SCHEMBL20477944 0.75 NPC1 (0.43)
SCHEMBL29504825 0.75 PLAU (0.43)
SCHEMBL31312839 0.73 PLAU (0.42)
Hydrochloric Acid SCHEMBL10824104 0.73 PLAU (0.42)
SCHEMBL8827973 0.73 PLAU (0.42)
SCHEMBL7466363 0.72 MEN1 (0.39)
SCHEMBL21800939 0.72 MAPT (0.47)
SCHEMBL519894 0.72 PLAU (0.41)
SCHEMBL7344776 0.70 PLAU (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7524 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118102889-A Organic compound 奇华顿股份有限公司 2024-05-28 CN claimed
WO-2024052511-A1 SYNTHESIS OF FLAVOR MODULATORS GIVAUDAN SA (CH) 2024-03-14 WO claimed
WO-2024027694-A1 PROTEIN DEGRADATION AGENT 苏州开拓药业股份有限公司 2024-02-08 WO claimed
CN-117377727-A Coating composition comprising polysulfide corrosion inhibitor PRC-迪索托国际公司 2024-01-09 CN claimed
WO-2023244554-A1 CYCLIC PEPTIDES FOR TRAPPING INTERLEUKIN-1 BETA MERCK SHARP & DOHME LLC (US) 2023-12-21 WO claimed
US-20230406885-A1 CYCLIC PEPTIDES FOR TRAPPING INTERLEUKIN-1 BETA MERCK SHARP & DOHME LLC (US) 2023-12-21 US claimed
US-20230219933-A1 STERICALLY SHIELDED HEPTAMETHINE CYANINE DYES UNIVERSITY OF NOTRE DAME DU LAC (US) 2023-07-13 US claimed
WO-2023077678-A1 SMALL MOLECULE COMPOUND TARGETING SRSF6 PROTEIN AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国药科大学 2023-05-11 WO claimed
EP-4139402-A1 STERICALLY SHIELDED HEPTAMETHINE CYANINE DYES University of Notre Dame du Lac (US) 2023-03-01 EP claimed
US-11584745-B2 Aromatic heterocyclic compound, intermediate thereof, preparation method therefor, and pharmaceutical composition and use thereof SHANGHAI YINGLI PHARMACEUTICAL CO., LTD (CN) 2023-02-21 US claimed
EP-0244836-B1 TRIPEPTIDE DERIVATIVES Dainippon Pharmaceutical Co., Ltd. (JP) 1993-08-18 EP claimed
EP-0552489-A2 Peptide, production and use thereof TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-07-28 EP claimed
US-5204458-A Reacting an allenyl beta-lactam with a nucleophilic agent OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1993-04-20 US claimed
EP-0532456-A1 1-Acylpiperidine derivatives and their use as substance P antagonists CIBA-GEIGY AG (CH) 1993-03-17 EP claimed
EP-0444451-A2 3-Arylcarbonyl-1H-indoles useful as therapeutic agents STERLING WINTHROP INC. (US) 1991-09-04 EP claimed
US-4914092-A ANTIULCER AGENTS SYNTHELABO (FR) 1990-04-03 US claimed
US-4826814-A INHIBITORS OF ANGIOTENSIN CONVERTING ENZYME DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1989-05-02 US claimed
EP-0244836-A2 Tripeptide derivatives Dainippon Pharmaceutical Co., Ltd. (JP) 1987-11-11 EP claimed
US-4460594-A CENTRAL NERVOUS SYSTEM DISORDERS BEECHAM GROUP P.L.C. (GB) 1984-07-17 US claimed
EP-0077607-A1 N-substituted 3-aryl piperidines and derivatives thereof BEECHAM GROUP PLC (GB) 1983-04-27 EP claimed