SCHEMBL170456

SCHEMBL170456

C1=CNc2ccccc2C1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 1/20 0.43
MAPT P10636 4/20 0.35
NPC1 O15118 2/20 0.35
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
AHR P35869 1/20 0.35
PDK2 Q15119 1/20 0.35
HSP90AA1 P07900 1/20 0.35
THRB P10828 1/20 0.35
HK1 P19367 1/20 0.35
MAPK1 P28482 1/20 0.35
RECQL P46063 1/20 0.35
RAB9A P51151 1/20 0.35
GALK1 P51570 1/20 0.35
BLM P54132 1/20 0.35
HKDC1 Q2TB90 1/20 0.35
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MAPK13 O15264 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29504825 1.00 PLAU (0.43) PLAUMAPTNPC1KDM4EMEN1
SCHEMBL8827973 0.98 PLAU (0.42) PLAUMAPTNPC1KDM4EMEN1
SCHEMBL31312839 0.98 PLAU (0.42) PLAUMAPTNPC1KDM4EMEN1
Hydrochloric Acid SCHEMBL10824104 0.98 PLAU (0.42) PLAUMAPTNPC1KDM4EMEN1
Alcohol SCHEMBL11070882 0.88 PLAU (0.36) PLAUMAPTGAABRD4CREBBP
Sulfuric Acid SCHEMBL9547403 0.88 PLAU (0.36) PLAUMAPTNPC1KDM4EAHR
Tetrahydrofuran SCHEMBL28561750 0.87 PLAU (0.35) PLAUMAPTNPC1KDM4EMEN1
Biphenyl SCHEMBL16782903 0.82 GAA (0.36) PLAUMAPTAHRPDK2GAA
Benzo[D]Oxazole SCHEMBL231922 0.79 NPC1 (0.33) PLAUNPC1RAB9A
Benzo[D]Thiazole SCHEMBL230803 0.78 ALDH1A1 (0.54) PLAUHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1497 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092924-A1 NON-ENZYMATIC GLOW ASSAYS UNIVERSITY OF HOUSTON SYSTEM (US) 2026-04-02 US claimed
EP-3476895-B1 PRECURSOR COMPOSITIONS FOR AN INSULATION, INSULATED ROCKET MOTORS, AND RELATED METHODS NORTHROP GRUMMAN SYSTEMS CORP (US) 2024-06-26 EP claimed
US-11876268-B2 Polymer electrolyte membrane with platelets XEROX CORPORATION (US) 2024-01-16 US claimed
US-20230340530-A1 Methods of Protecting RNA PFIZER INC. (US) 2023-10-26 US claimed
US-20230287848-A1 PRECURSOR COMPOSITIONS FOR AN INSULATION AND RELATED METHODS NORTHROP GRUMMAN SYSTEMS CORP (US) 2023-09-14 US claimed
CN-111170940-B Synthesis method of 1, 4-dihydroquinoline and 1, 4-dihydropyridine compounds and application of compounds in antitumor drugs 天津科技大学 2023-09-05 CN claimed
CN-115947683-A Synthesis method of tetrahydroquinoline and derivatives thereof 湖南工程学院 2023-04-11 CN claimed
US-11613649-B2 Thermally-rearranged polymer blends for gas separation membranes BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-03-28 US claimed
EP-4143172-A1 ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES Syddansk Universitet (DK) 2023-03-08 EP claimed
US-20220416283-A1 POLYMER ELECTROLYTE MEMBRANE WITH PLATELETS PALO ALTO RESEARCH CENTER INCORPORATED (US) 2022-12-29 US claimed
US-4828733-A Copper salts of hindered phenolic carboxylates and lubricants and fuels containing same MOBIL OIL CORPORATION (US) 1989-05-09 US claimed
US-4810364-A REMOVAL OF SULFUR, NITROGEN AND OXYGEN FROM AROMATICS PHILLIPS PETROLEUM COMPANY (US) 1989-03-07 US claimed
EP-0293071-A1 Redox amino acids and peptides containing them UNIVERSITY OF FLORIDA (US) 1988-11-30 EP claimed
US-4784958-A CARDIOVASCULAR DISORDERS GLOSSMANN HARTMUT (DE) 1988-11-15 US claimed
EP-0239129-A2 Hydroquinoline compounds, compositions containing same and processes for preparing same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1987-09-30 EP claimed
US-4624977-A NATURAL OR SYNTHETIC RUBBER DENATURED NITROSOQUINOLINE, CARBON BLACK BRIDGESTONE CORPORATION (JP) 1986-11-25 US claimed
EP-0107938-A1 Quinoline or hydroquinoline compounds, their preparation and pharmaceutical compostions comprising them KOWA COMPANY, LTD. (JP) 1984-05-09 EP claimed
US-4209597-A AZO CROSSLINKER FOR RAPID CURE AB GUSTAVSBERG (SE) 1980-06-24 US claimed
US-4095015-A IRON, COMPLEXING AGENTS, ELE FACES AB S. T. POWERCELL (SW) 1978-06-13 US claimed
US-4028362-A VAPORIZATION OF 2-(BETA-CYANOETHYL)-CYCLOHEXANONES, DEHYDROGENATION CATALYST STAMICARBON B. V. (NL) 1977-06-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092924-A1 NON-ENZYMATIC GLOW ASSAYS LPO, HAO2, PPOX PLAU 490/4885MAPT 2971/4885NPC1 4173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.