SCHEMBL19677797

CC[C@H]1O[C@@H](n2cc(C)c(N)nc2=O)C[C@H]1OP(=O)(S)OC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)C[C@H]1OP(=O)(S)OC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)C[C@H]1OP(=O)(S)OC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)C[C@H]1OP(=O)(S)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)C[C@H]1OP(=O)(S)OC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)C[C@H]1OP(=O)(S)OC[C@H]1O[C@@H](n2cc(C)c(N)nc2=O)C[C@H]1OP(=O)(O)S

nearest known ligand 0.57

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	DTYMK	P23919	4/20	0.57

▸	TERT	O14746	2/20	0.50

▸	F2	P00734	1/20	0.45

▸	TK1	P04183	3/20	0.45

▸	POLB	P06746	1/20	0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL26488844	0.95	DTYMK (0.54)	DTYMKTERTF2TK1POLB
SCHEMBL26401731	0.95	DTYMK (0.54)	DTYMKTERTF2TK1POLB
SCHEMBL20024801	0.95	DTYMK (0.54)	DTYMKTERTF2TK1POLB
SCHEMBL26276397	0.95	DTYMK (0.54)	DTYMKTERTF2TK1POLB
SCHEMBL18472073	0.95	DTYMK (0.54)	DTYMKTERTF2TK1POLB
SCHEMBL18159196	0.95	DTYMK (0.54)	DTYMKTERTF2TK1POLB
SCHEMBL26220660	0.95	DTYMK (0.54)	DTYMKTERTF2TK1POLB
SCHEMBL26220986	0.95	DTYMK (0.54)	DTYMKTERTF2TK1POLB
SCHEMBL17775306	0.95	DTYMK (0.54)	DTYMKTERTF2TK1POLB
SCHEMBL27000712	0.95	DTYMK (0.54)	DTYMKTERTF2TK1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20170349897-A1	COMPOSITIONS FOR MODULATING C9ORF72 EXPRESSION	IONIS PHARMACEUTICALS, INC. (US)	2017-12-07	—	—	US	disclosed