Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17462518 | 0.88 | USP2 (0.44) | USP2SMN1; SMN2PIK3CDESR2NR1H2 | |
| SCHEMBL17462516 | 0.87 | ESR2 (0.45) | USP2SMN1; SMN2PIK3CDESR2NR1H2 | |
| SCHEMBL19679351 | 0.86 | USP2 (0.43) | USP2SMN1; SMN2PIK3CDESR2NR1H2 | |
| SCHEMBL17453606 | 0.85 | USP2 (0.40) | USP2SMN1; SMN2PIK3CDESR2NR1H2 | |
| SCHEMBL19679350 | 0.84 | USP2 (0.41) | USP2SMN1; SMN2PIK3CDESR2NR1H2 | |
| SCHEMBL17462514 | 0.84 | USP2 (0.41) | USP2SMN1; SMN2PIK3CDESR2NR1H2 | |
| SCHEMBL17462515 | 0.83 | NR1H2 (0.43) | USP2SMN1; SMN2PIK3CDESR2NR1H2 | |
| SCHEMBL16461039 | 0.81 | ESR2 (0.44) | USP2SMN1; SMN2PIK3CDESR2NR1H2 | |
| SCHEMBL19684711 | 0.81 | PIK3CD (0.36) | USP2SMN1; SMN2PIK3CDESR2NR1H2 | |
| SCHEMBL17463415 | 0.80 | USP2 (0.38) | USP2SMN1; SMN2PIK3CDESR2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170348313-A1 | SUBSTITUTED CARBONUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER INC. (US) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170348313-A1 | SUBSTITUTED CARBONUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS | DUT, NCL, TYMP | USP2 3416/4885SMN1; SMN2 1375/4885PIK3CD 818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.