Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19246887 | 0.93 | TSHR (0.38) | TSHRMAPTKMT2AMEN1CSF1R | |
| SCHEMBL20030086 | 0.92 | PIM1 (0.39) | TSHRMAPTKMT2AMEN1CSF1R | |
| SCHEMBL26741320 | 0.92 | TSHR (0.34) | TSHRMAPTKMT2AMEN1CSF1R | |
| SCHEMBL19246994 | 0.91 | TSHR (0.38) | TSHRMAPTKMT2AMEN1CSF1R | |
| SCHEMBL26741271 | 0.90 | TSHR (0.34) | TSHRMAPTKMT2AMEN1CSF1R | |
| SCHEMBL16905618 | 0.89 | TSHR (0.44) | TSHRMAPTKMT2AMEN1CSF1R | |
| SCHEMBL19679641 | 0.86 | MAPT (0.39) | TSHRMAPTKMT2AMEN1CSF1R | |
| SCHEMBL26741934 | 0.86 | ABCG2 (0.34) | TSHRMAPTKMT2AMEN1CSF1R | |
| SCHEMBL25147252 | 0.85 | KDM4E (0.40) | TSHRMAPTKMT2AMEN1CSF1R | |
| SCHEMBL20024809 | 0.85 | KDM4E (0.36) | TSHRMAPTKMT2AMEN1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170352447-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME | SFC CO., LTD. (KR) | 2017-12-07 | — | — | US | disclosed |
| US-20170352447-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME | SFC CO., LTD. (KR) | 2017-12-07 | — | — | US | disclosed |