Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 9/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24746376 | 0.93 | PIM1 (0.37) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL19679645 | 0.92 | TSHR (0.37) | ALDH1A1TSHRHPGDMAPTKMT2A | |
| SCHEMBL20030085 | 0.89 | KDM4E (0.38) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL20029924 | 0.89 | KDM4E (0.38) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL16905618 | 0.88 | TSHR (0.44) | ALDH1A1TSHRHPGDMAPTKMT2A | |
| SCHEMBL19246994 | 0.88 | TSHR (0.38) | ALDH1A1TSHRHPGDMAPTKMT2A | |
| SCHEMBL19246887 | 0.88 | TSHR (0.38) | ALDH1A1TSHRHPGDMAPTKMT2A | |
| SCHEMBL20024252 | 0.87 | PIM1 (0.38) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL20024249 | 0.87 | PIM1 (0.38) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL17087599 | 0.87 | KDM4E (0.38) | ALDH1A1TSHRHPGDMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12030890-B2 | Compounds with diazadibenzofurane or diazadibenzothiophene structures | MERCK PATENT GMBH (DE) | 2024-07-09 | — | — | US | disclosed |
| US-12030890-B2 | Compounds with diazadibenzofurane or diazadibenzothiophene structures | MERCK PATENT GMBH (DE) | 2024-07-09 | — | — | US | disclosed |
| US-11530224-B2 | Compounds with diazadibenzofurane or diazadibenzothiophene structures | MERCK PATENT GMBH (DE) | 2022-12-20 | — | — | US | disclosed |
| EP-3519417-B1 | COMPOUNDS WITH DIAZADIBENZOFURANE OR DIAZADIBENZOTHIOPHENE STRUCTURES | MERCK PATENT GMBH (DE) | 2021-09-08 | — | — | EP | disclosed |
| WO-2018060307-A1 | COMPOUNDS WITH DIAZADIBENZOFURANE OR DIAZADIBENZOTHIOPHENE STRUCTURES | MERCK PATENT GMBH (DE) | 2018-04-05 | — | — | WO | disclosed |
| US-9238815-B2 | Compositions and methods for inhibiting human host factors required for influenza virus replication | Icahn School of Medicine at Mounta Sinai (US) | 2016-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12030890-B2 | Compounds with diazadibenzofurane or diazadibenzothiophene structures | DDT, ESD, DBF4 | PIM1 344/4885CSNK2A2 4573/4885CSNK2B 4537/4885 |
| US-11530224-B2 | Compounds with diazadibenzofurane or diazadibenzothiophene structures | DDT, ESD, DBF4 | PIM1 344/4885CSNK2A2 4573/4885CSNK2B 4537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.