Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16905826 | 0.90 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNAHPGDALDH1A1MEN1 | |
| SCHEMBL20024416 | 0.87 | PLA2G2A (0.36) | SMN1; SMN2LMNAHPGDALDH1A1MEN1 | |
| SCHEMBL24746427 | 0.85 | SMN1; SMN2 (0.36) | SMN1; SMN2LMNAHPGDALDH1A1MEN1 | |
| SCHEMBL19247405 | 0.79 | TSHR (0.36) | AHRSMN1; SMN2LMNAHPGDALDH1A1 | |
| SCHEMBL19246479 | 0.79 | SMN1; SMN2 (0.34) | AHRSMN1; SMN2LMNAHPGDALDH1A1 | |
| SCHEMBL19162400 | 0.79 | SMN1; SMN2 (0.32) | SMN1; SMN2LMNAHPGDALDH1A1MEN1 | |
| SCHEMBL19163040 | 0.79 | SMN1; SMN2 (0.32) | SMN1; SMN2LMNAHPGDALDH1A1MEN1 | |
| SCHEMBL19163386 | 0.78 | SMN1; SMN2 (0.32) | SMN1; SMN2LMNAHPGDALDH1A1MEN1 | |
| SCHEMBL19161971 | 0.78 | SMN1; SMN2 (0.32) | SMN1; SMN2LMNAHPGDALDH1A1MEN1 | |
| SCHEMBL19679749 | 0.78 | AHR (0.37) | AHRSMN1; SMN2LMNAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170352447-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME | SFC CO., LTD. (KR) | 2017-12-07 | — | — | US | disclosed |
| US-20170352447-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME | SFC CO., LTD. (KR) | 2017-12-07 | — | — | US | disclosed |