Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17851654 | 1.00 | HRH4 (0.31) | HRH4 | |
| SCHEMBL19744060 | 1.00 | HRH4 (0.31) | HRH4 | |
| SCHEMBL26465502 | 0.92 | PDE10A (0.30) | — | |
| SCHEMBL26095472 | 0.92 | PDE10A (0.30) | — | |
| SCHEMBL19680469 | 0.92 | PDE10A (0.30) | — | |
| SCHEMBL19744239 | 0.91 | PDE10A (0.30) | — | |
| SCHEMBL17851638 | 0.91 | PDE10A (0.30) | — | |
| SCHEMBL19680464 | 0.91 | PDE10A (0.30) | — | |
| SCHEMBL19743689 | 0.89 | PIK3CA (0.34) | — | |
| SCHEMBL19680460 | 0.89 | PIK3CA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10240043-B2 | Use for dyeing keratin fibres of a compound of azomethine type bearing two pyrazolopyridine units | L'OREAL (FR) | 2019-03-26 | — | — | US | disclosed |
| US-20170349753-A1 | USE FOR DYEING KERATIN FIBRES OF A COMPOUND OF AZOMETHINE TYPE BEARING TWO PYRAZOLOPYRIDINE UNITS | L'OREAL (FR) | 2017-12-07 | — | — | US | disclosed |
| US-20170349753-A1 | USE FOR DYEING KERATIN FIBRES OF A COMPOUND OF AZOMETHINE TYPE BEARING TWO PYRAZOLOPYRIDINE UNITS | L'OREAL (FR) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349753-A1 | USE FOR DYEING KERATIN FIBRES OF A COMPOUND OF AZOMETHINE TYPE BEARING TWO PYRAZOLOPYRIDINE UNITS | KRT18, DSP, TMPO | HRH4 1891/4885 |
| US-10240043-B2 | Use for dyeing keratin fibres of a compound of azomethine type bearing two pyrazolopyridine units | KRT18, DSP, TMPO | HRH4 1891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.