Sugi Predict

Sugi Predict / Targets / DSP

DSP

Desmoplakin · P15924 · DSP on Sugi Atlas →

0 patent compounds predicted against DSP, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to DSP by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Targeted Therapy With Glycogen Synthase Kinase-3 Inhibition for Arrhythmogenic Cardiomyopathy PHASE2RECRUITING
Phase Ib Study of Erlotinib Prior to Surgery in Patients With Head and Neck Cancer PHASE1COMPLETED
Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy nanCOMPLETED
DNA Analysis From Isolated Cardiomyocytes in the Molecular Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia nanCOMPLETED
Mayo AVC Registry and Biobank nanRECRUITING
Evaluation of Desmoglein-3 Autoantibodies in the Tissues of Oral Lichen Planus and Correlation with Disease Severity nanNOT_YET_RECRUITING
Local Inflammation in Arrhythmogenic Right Ventricular Cardiomyopathy nanRECRUITING
FAPI PET/CT Imaging in Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) (FAPI-ARVC)) nanRECRUITING
Profiling Gingival Crevicular Fluid β-Catenin Level With 8-OHdG and Total Antioxidants Capacity During Healing of Periodontal Pockets: A 3-month Clinical Trial nanNOT_YET_RECRUITING
Multidisciplinary Study of Right Ventricular Dysplasia nanCOMPLETED
National ARVC Data Registry and Bio Bank nanCOMPLETED
Artificial Intelligence for the Prioritization of Genetic Background in Brugada Syndrome nanCOMPLETED
Epithelial Mesenchymal Transition and Periodontitis nanUNKNOWN
CDH1 Germline Mutations in Lobular Breast Cancer nanCOMPLETED
Signs and Symptoms Associated With Molecular Defects in Genetically Inherited Heart Disease nanCOMPLETED
DMD Gene Variants and Cardiac Dysfunction in Young Males With Dystrophinopathies nanRECRUITING
PKP2-ACM Natural History Study nanRECRUITING
Muscle Wasting in Cancer (MWIC) nanCOMPLETED
Mapping Novel Disease Genes for Dilated Cardiomyopathy nanCOMPLETED
Evaluation of the Clinical Course of NERD and Assessment of the Esophageal Mucosa Resistance nanACTIVE_NOT_RECRUITING
Distribution of Cell-cell Junction Proteins in Arrhythmic Disorders nanRECRUITING
Cardiac Biomarkers in Pediatric Cardiomyopathy (PCM Biomarkers) nanUNKNOWN
Epithelial Mesenchymal Transition Markers in OSMF nanCOMPLETED
Genetics of Ehlers-Danlos Syndrome nanCOMPLETED
The Activation of Hippo Pathway in Nasal Polyps nanUNKNOWN
Clinical and Genetic Examinations of Dilated Cardiomyopathy nanCOMPLETED
The Role of Biomarkers in Inherited Cardiac Conditions nanWITHDRAWN
Comparing Pulmonary Vein Isolation to Pulmonary Vein Isolation + OPTIMA Ablation in Patients Undergoing Ablation for Atrial Fibrillation nanCOMPLETED
Registry of Unexplained Cardiac Arrest nanCOMPLETED
Genotype-phenotype Correlation in Junctional Epidermolysis Bullosa nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a DSP binder may also engage these)

ProteinNameSimilarity
E9Q557 — 1.000 E9Q557 →
F1LMV6 — 0.999 F1LMV6 →
A0A8M2BID5 — 0.995 A0A8M2BID5 →
Q03001 — 0.990 Q03001 →
Q0KL02 — 0.989 Q0KL02 →
Q5GN48 — 0.987 Q5GN48 →
Q91ZU6 — 0.987 Q91ZU6 →
Q8NF91 — 0.986 Q8NF91 →
P11532 — 0.986 P11532 →
O75962 — 0.985 O75962 →
MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 0.984 landscape →
Q6ZWR6 — 0.984 Q6ZWR6 →
O60437 — 0.984 O60437 →
O97592 — 0.984 O97592 →
Q9VDW6 — 0.983 Q9VDW6 →
Q9QXS1 — 0.983 Q9QXS1 →
D3ZHV2 — 0.983 D3ZHV2 →
Q9QXZ0 — 0.983 Q9QXZ0 →
F1M0Z1 — 0.983 F1M0Z1 →
A2CG49 — 0.983 A2CG49 →
P10911 — 0.982 P10911 →
O43150 — 0.982 O43150 →
P11533 — 0.982 P11533 →
A0A8M9PQ61 — 0.981 A0A8M9PQ61 →
O60229 — 0.981 O60229 →
P30427 — 0.981 P30427 →
Q1LUA6 — 0.981 Q1LUA6 →
Q9R269 — 0.981 Q9R269 →
Q9JI55 — 0.980 Q9JI55 →
UTRN Utrophin 0.980 landscape →