Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 8/20 | 0.69 |
| ▸ | HTR3A | P46098 | 3/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.42 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1967348 | 1.00 | CHRNA7 (0.69) | CHRNA7HTR3ANPC1RAB9AGSK3B | |
| SCHEMBL1965172 | 1.00 | CHRNA7 (0.69) | CHRNA7HTR3ANPC1RAB9AGSK3B | |
| SCHEMBL1963244 | 0.99 | CHRNA7 (0.70) | CHRNA7HTR3ANPC1RAB9AGSK3B | |
| SCHEMBL1965004 | 0.99 | CHRNA7 (0.70) | CHRNA7HTR3ANPC1RAB9AGSK3B | |
| SCHEMBL1969429 | 0.91 | CHRNA7 (0.70) | CHRNA7HTR3ANPC1RAB9AGSK3B | |
| SCHEMBL1964774 | 0.91 | CHRNA7 (0.70) | CHRNA7HTR3ANPC1RAB9AGSK3B | |
| SCHEMBL1965143 | 0.91 | CHRNA7 (0.70) | CHRNA7HTR3ANPC1RAB9AGSK3B | |
| SCHEMBL1966222 | 0.90 | CHRNA7 (0.66) | CHRNA7HTR3APRKAB2PRKAG1PRKAA2 | |
| SCHEMBL1964032 | 0.90 | CHRNA7 (0.66) | CHRNA7HTR3APRKAB2PRKAG1PRKAA2 | |
| SCHEMBL261046 | 0.87 | CHRNA7 (0.72) | CHRNA7HTR3AGSK3BHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336128-A1 | Benzoisothiazoles and preparation and uses thereof | Memory Pharmaceuticals Corporation (US) | 2011-06-22 | — | — | EP | disclosed |